Items where authors include "Murdoch, C."
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Farr, N.T.H. orcid.org/0000-0001-6761-3600, Workman, V.L., Saad, S. et al. (6 more authors) (2024) Uncovering the relationship between macrophages and polypropylene surgical mesh. Biomaterials Advances, 159. 213800. ISSN 2772-9508
Edmans, J.G. orcid.org/0000-0002-4539-9145, Murdoch, C. orcid.org/0000-0001-9724-122X, Hatton, P.V. orcid.org/0000-0001-5234-1104 et al. (4 more authors) (2024) Bioactive protein and peptide release from a mucoadhesive electrospun membrane. Biomedical Materials & Devices, 2 (1). pp. 444-453. ISSN 2731-4812
Edmans, J.G., Harrison, S., Hatton, P.V. et al. (3 more authors) (2024) Electrospinning polymersomes into bead-on-string polyethylene oxide fibres for the delivery of biopharmaceuticals to mucosal epithelia. Biomaterials Advances, 157. 213734. ISSN 2772-9508
Harding, A.L., Colley, H.E. orcid.org/0000-0003-0053-7468, Barragan Vazquez, I. et al. (5 more authors) (2022) c‐Src activation as a potential marker of chemical‐induced skin irritation using tissue‐engineered skin equivalents. Experimental Dermatology. ISSN 0906-6705
Edmans, J.G., Ollington, B., Colley, H.E. orcid.org/0000-0003-0053-7468 et al. (5 more authors) (2022) Electrospun patch delivery of anti-TNFα F(ab) for the treatment of inflammatory oral mucosal disease. Journal of Controlled Release, 350. pp. 146-157. ISSN 0168-3659
Farrugia, C., Stafford, G.P., Gains, A.F. et al. (2 more authors) (2022) Fusobacterium nucleatum mediates endothelial damage and increased permeability following single species and polymicrobial infection. Journal of Periodontology, 93 (9). pp. 1421-1433. ISSN 0022-3492
Heath, J.P., Hunter, K.D., Murdoch, C. orcid.org/0000-0001-9724-122X et al. (1 more author) (2022) Computational modelling for electrical impedance spectroscopy-based diagnosis of oral potential malignant disorders (OPMD). Sensors, 22 (15). 5913.
El-Howati, A., Thornhill, M. orcid.org/0000-0003-0681-4083, Colley, H. et al. (1 more author) (2022) Immune mechanisms in oral lichen plants. Oral Diseases. ISSN 1354-523X
Niklander, S.E., Murdoch, C. orcid.org/0000-0001-9724-122X and Hunter, K.D. orcid.org/0000-0002-7873-0877 (2021) IL-1/IL-1R Signaling in head and neck cancer. Frontiers in Oral Health, 2. 722676.
Ollington, B., Colley, H.E. orcid.org/0000-0003-0053-7468 and Murdoch, C. orcid.org/0000-0001-9724-122X (2021) Immuno-responsive tissue engineered oral mucosal equivalents containing macrophages. Tissue Engineering Part C: Methods, 27 (8). pp. 462-471. ISSN 1937-3384
West, H., Roberts, F., Sweeney, P. et al. (6 more authors) (2021) A mathematical investigation into the uptake kinetics of nanoparticles in vitro. PLoS ONE, 16 (7). e0254208.
Harding, A.L., Murdoch, C. orcid.org/0000-0001-9724-122X, Danby, S. et al. (6 more authors) (2021) Determination of chemical irritation potential using a defined gene signature set on tissue-engineered human skin equivalents. JID Innovations, 1 (2). 100011. ISSN 2667-0267
McRae, M.P., Kerr, A.R., Janal, M.N. et al. (14 more authors) (2021) Nuclear F-actin cytology in oral dysplasia and oral squamous cell carcinoma. Journal of Dental Research, 100 (5). pp. 479-486. ISSN 0022-0345
Said, Z., Murdoch, C. orcid.org/0000-0001-9724-122X, Hansen, J. et al. (2 more authors) (2021) Corticosteroid delivery using oral mucosa equivalents for the treatment of inflammatory mucosal diseases. European Journal of Oral Sciences, 129 (2). e12761. ISSN 0909-8836
Farrugia, C. orcid.org/0000-0003-1318-8885, Stafford, G.P., Potempa, J. et al. (4 more authors) (2021) Mechanisms of vascular damage by systemic dissemination of the oral pathogen Porphyromonas gingivalis. The FEBS Journal, 288 (5). pp. 1479-1495. ISSN 1742-464X
Al-Sahaf, S., Hendawi, N.B., Ollington, B. et al. (4 more authors) (2021) Increased abundance of tumour-associated neutrophils in HPV-negative compared to HPV-positive oropharyngeal squamous cell carcinoma is mediated by IL-1R signalling. Frontiers in Oral Health, 2. 604565. ISSN 2673-4842
Farrugia, C. orcid.org/0000-0003-1318-8885, Stafford, G.P. and Murdoch, C. orcid.org/0000-0001-9724-122X (2020) Porphyromonas gingivalis outer membrane vesicles increase vascular permeability. Journal of Dental Research, 99 (13). pp. 1494-1501. ISSN 0022-0345
Mouhat, M., Moorehead, R. and Murdoch, C. orcid.org/0000-0001-9724-122X (2020) In vitro Candida albicans biofilm formation on different titanium surface topographies. Biomaterial Investigations in Dentistry, 7 (1). pp. 146-157. ISSN 2641-5275
Ferreira, S.B.D.S., Hoshino, L.V.D.C., Slowik, K. et al. (4 more authors) (2020) Mucoadhesive emulgel systems containing curcumin for oral squamous cell carcinoma treatment: from pre-formulation to cytotoxicity in tissue-engineering oral mucosa. European Journal of Pharmaceutical Sciences, 151. 105372. ISSN 0928-0987
Edmans, J.G., Murdoch, C. orcid.org/0000-0001-9724-122X, Santocildes-Romero, M.E. et al. (3 more authors) (2020) Incorporation of lysozyme into a mucoadhesive electrospun patch for rapid protein delivery to the oral mucosa. Materials Science and Engineering: C, 112. 110917. ISSN 0928-4931
Clitherow, K.H., Binaljadm, T.M., Hansen, J. et al. (3 more authors) (2020) Medium-chain fatty acids released from polymeric electrospun patches inhibit Candida albicans growth and reduce the biofilm viability. ACS Biomaterials Science & Engineering, 6 (7). pp. 4087-4095. ISSN 2373-9878
Edmans, J.G., Clitherow, K.H., Murdoch, C. orcid.org/0000-0001-9724-122X et al. (3 more authors) (2020) Mucoadhesive electrospun fibre-based technologies for oral medicine. Pharmaceutics, 12 (6). 504. ISSN 1999-4923
Leedale, J.A., Kyffin, J.A., Harding, A.L. et al. (6 more authors) (2020) Multiscale modelling of drug transport and metabolism in liver spheroids. Interface Focus, 10 (2). ISSN 2042-8898
McRae, M., Modak, S., Simmons, G. et al. (10 more authors) (2020) Point-of-care oral cytology tool for the screening and assessment of potentially malignant oral lesions. Cancer Cytopathology, 128 (3). pp. 207-220. ISSN 1934-662X
Ferreira, S.B.D.S., Braga, G., Oliveira, É.L. et al. (8 more authors) (2019) Design of a nanostructured mucoadhesive system containing curcumin for buccal application : from physicochemical to biological aspects. Beilstein Journal of Nanotechnology, 10. pp. 2304-2328. ISSN 2190-4286
Swidergall, M., Khalaji, M., Solis, N.V. et al. (7 more authors) (2019) Candidalysin is required for neutrophil recruitment and virulence during systemic Candida albicans infection. The Journal of Infectious Diseases, 220 (9). pp. 1477-1488. ISSN 0022-1899
Leedale, J., Colley, H.E. orcid.org/0000-0003-0053-7468, Gaskell, H. et al. (5 more authors) (2019) In silico-guided optimisation of oxygen gradients in hepatic spheroids. Computational Toxicology, 12. 100093. ISSN 2468-1113
Sah, P., Patel, P., Chandrashekar, C. et al. (7 more authors) (2019) Oral candidal carriage correlates with CD4+ cell count but not with HIV and highly active antiretroviral therapy status. Journal of Investigative and Clinical Dentistry, 10 (4). e12438. ISSN 2041-1618
Al-Zubidi, M., Widziolek, M., Court, E.K. et al. (10 more authors) (2019) Identification of novel bacteriophages with therapeutic potential targeting Enterococcus faecalis. Infection and Immunity, 87 (11). e00512-e00519. ISSN 0019-9567
Clitherow, K.H., Murdoch, C. orcid.org/0000-0001-9724-122X, Spain, S.G. orcid.org/0000-0001-7241-5713 et al. (7 more authors) (2019) Mucoadhesive electrospun patch delivery of lidocaine to the oral mucosa and investigation of spatial distribution in tissue using MALDI-mass spectrometry imaging. Molecular Pharmaceutics, 16 (9). pp. 3948-3956. ISSN 1543-8384
Kyffin, J.A., Cox, C.R., Leedale, J. et al. (5 more authors) (2019) Preparation of primary rat hepatocyte spheroids utilizing the liquid‐overlay technique. Current Protocols in Toxicology, 81 (1). e87. ISSN 1934-9254
Tomlinson, L., Lu, Z.Q., Bentley, R.A. et al. (6 more authors) (2019) Attenuation of doxorubicin-induced cardiotoxicity in a human in vitro cardiac model by the induction of the NRF-2 pathway. Biomedicine and Pharmacotherapy, 112. 108637. ISSN 0753-3322
Mariño-Crespo, Ó., Cuevas-Álvarez, E., Harding, A.L. et al. (3 more authors) (2019) Haptoglobin expression in human colorectal cancer. Histology and Histopathology, 34 (8). pp. 953-963. ISSN 0213-3911
Kyffin, J.A., Sharma, P., Leedale, J. et al. (5 more authors) (2019) Characterisation of a functional rat hepatocyte spheroid model. Toxicology in Vitro, 55. pp. 160-172. ISSN 0887-2333
Al-Sahaf, S., Hunter, K.D. orcid.org/0000-0002-7873-0877, Bolt, R. et al. (2 more authors) (2019) The IL-1/IL-1R axis induces greater fibroblast-derived chemokine release in human papillomavirus-negative compared to positive oropharyngeal cancer. International Journal of Cancer, 144 (2). pp. 334-344. ISSN 0020-7136
Hearnden, V., Murdoch, C., D'Apice, K. et al. (3 more authors) (2018) Oral human papillomavirus infection in England and associated risk factors: a case-control study. BMJ Open, 8 (8). e022497. ISSN 2044-6055
Leedale, J. orcid.org/0000-0001-9010-4126, Sharkey, K.J., Colley, H.E. orcid.org/0000-0003-0053-7468 et al. (7 more authors) (2018) A Combined In Vitro/In Silico Approach to Identifying Off-Target Receptor Toxicity. iScience, 4. pp. 84-96. ISSN 2589-0042
Colley, H.E. orcid.org/0000-0003-0053-7468, Said, Z., Santocildes-Romero, M.E. et al. (7 more authors) (2018) Pre-clinical evaluation of novel mucoadhesive bilayer patches for local delivery of clobetasol-17-propionate to the oral mucosa. Biomaterials, 178. pp. 134-146. ISSN 0142-9612
Smith, S.A., Colley, H.E., Sharma, P. et al. (5 more authors) (2018) Expression and enzyme activity of Cytochrome P450 enzymes CYP3A4 and CYP3A5 in human skin and tissue engineered skin equivalents. Experimental Dermatology, 27 (5). pp. 473-475. ISSN 0906-6705
Hearnden, V. orcid.org/0000-0003-0838-7783, Powers, H.J., Elmogassabi, A. et al. (2 more authors) (2018) Methyl-donor depletion of head and neck cancer cells in vitro establishes a less aggressive tumour cell phenotype. European Journal of Nutrition, 57 (4). pp. 1321-1332. ISSN 1436-6207
Walladbegi, J., Smith, S.A., Grayson, A. et al. (3 more authors) (2018) Cooling of the oral mucosa to prevent adverse effects of chemotherapeutic agents - an in vitro study. Journal of Oral Pathology and Medicine, 47 (5). pp. 477-483. ISSN 0904-2512
Morse, D.J., Wilson, M.J., Wei , X. et al. (4 more authors) (2018) Denture-associated biofilm infection in three-dimensional oral mucosal tissue models. Journal of medical microbiology, 67 (3). pp. 364-375. ISSN 0022-2615
Grayson, A., Hearnden, V.L. orcid.org/0000-0003-0838-7783, Bolt, R. et al. (3 more authors) (2018) Use of a Rho kinase inhibitor to increase human tonsil keratinocyte longevity for three-dimensional, tissue engineered tonsil epithelium equivalents. Journal of Tissue Engineering and Regenerative Medicine, 12 (3). e1636-e1646. ISSN 1932-6254
Kyffin, J.A., Sharma, P., Leedale, J. et al. (4 more authors) (2018) Impact of cell types and culture methods on the functionality of in vitro liver systems - A review of cell systems for hepatotoxicity assessment. Toxicol In Vitro, 48. pp. 262-275.
Bolt, R., Foran, B., Murdoch, C. orcid.org/0000-0001-9724-122X et al. (3 more authors) (2018) HPV-negative, but not HPV-positive, oropharyngeal carcinomas induce fibroblasts to support tumour invasion through micro-environmental release of HGF and IL-6. Carcinogenesis, 39 (2). pp. 170-179. ISSN 0143-3334
Madden, J.C., Webb, S., Enoch, S.J. et al. (6 more authors) (2017) In silico prediction of skin metabolism and its implication in toxicity assessment. Computational Toxicology, 3. pp. 44-57. ISSN 2468-1113
Santocildes-Romero, M.E., Hadley, L., Clitherow, K.H. et al. (5 more authors) (2017) Fabrication of electrospun mucoadhesive membranes for therapeutic applications in oral medicine. ACS Applied Materials and Interfaces, 9 (13). pp. 11557-11567. ISSN 1944-8244
Naylor, K.L., Widziolek, M., Hunt, S. et al. (6 more authors) (2017) Role of OmpA2 surface regions of Porphyromonas gingivalis in host-pathogen interactions with oral epithelial cells. MicrobiologyOpen, 6 (1). e00401. ISSN 2045-8827
Jennings, L., Colley, H.E. orcid.org/0000-0003-0053-7468, Ong, J. et al. (5 more authors) (2016) Development and characterisation of in vitro human oral mucosal equivalents derived from immortalised oral keratinocytes. Tissue Eng Part C Methods, 22 (12). pp. 1108-1117. ISSN 1937-3384
Widziolek, M., Prajsnar, T.K., Tazzyman, S. et al. (3 more authors) (2016) Zebrafish as a new model to study effects of periodontal pathogens on cardiovascular diseases. Scientific Reports, 6. p. 36023. ISSN 2045-2322
Abram, T.J., Floriano, P.N., Christodoulides, N. et al. (30 more authors) (2016) ‘Cytology-on-a-chip’ based sensors for monitoring of potentially malignant oral lesions. Oral Oncology, 60. pp. 103-111. ISSN 1368-8375
Gaskell, H., Sharma, P., Colley, H.E. orcid.org/0000-0003-0053-7468 et al. (3 more authors) (2016) Characterization of a functional C3A liver spheroid model. Toxicology Research. ISSN 2045-452X
Speight, P.M. orcid.org/0000-0001-6459-1370, Abram, T.J., Floriano, P.N. et al. (21 more authors) (2015) Interobserver agreement in dysplasia grading: toward an enhanced gold standard for clinical pathology trials. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 120 (4). 474-482.e2. ISSN 2212-4403
Muthana, M., Kennerley, A.J., Hughes, R. et al. (12 more authors) (2015) Directing cell therapy to anatomic target sites in vivo with magnetic resonance targeting. Nature Communications, 6. 8009.
Darda, L., Hakami, F., Morgan, R. et al. (3 more authors) (2015) The Role of HOXB9 and miR-196a in Head and Neck Squamous Cell Carcinoma. PLoS One, 10 (4). e0122285 . - .
Boadi, J., Fernandes, J., Mittar, S. et al. (7 more authors) (2015) Imaging of 3D tissue-engineered models of oral cancer using 890 and 1300 nm optical coherence tomography. Sovremennye Tehnologii v Medicine, 7 (1). 60 - 67. ISSN 2076-4243
Tazzyman, S., Murdoch, C., Yeomans, J. et al. (2 more authors) (2014) Macrophage-mediated response to hypoxia in disease. Hypoxia, 2. pp. 185-196.
Murdoch, C., Brown, B.H., Hearnden, V. et al. (7 more authors) (2014) Use of electrical impedance spectroscopy to detect malignant and potentially malignant oral lesions. International Journal of Nanomedicine, 9 (1). pp. 4521-4532. ISSN 1178-2013
Sorrell, I., Shipley, R.J., Hearnden, V. et al. (4 more authors) (2014) Combined mathematical modelling and experimentation to predict polymersome uptake by oral cancer cells. Nanomedicine: Nanotechnology, Biology and Medicine, 10 (2). pp. 339-348. ISSN 1549-9634
Stafford, P., Higham, J., Pinnock, A. et al. (4 more authors) (2013) Gingipain-dependent degradation of mammalian target of rapamycin pathway proteins by the periodontal pathogen Porphyromonas gingivalis during invasion. Molecular Oral Microbiology, 28 (5). pp. 366-378. ISSN 2041-1006
West, L., Lowman, D.W., Mora-Montes, H.M. et al. (6 more authors) (2013) Differential virulence of Candida glabrata glycosylation mutants. Journal of Biological Chemistry, 288 (30). 22006. ISSN 0021-9258
Elbarghati, L., Azzouz, L., Murdoch, C. orcid.org/0000-0001-9724-122X et al. (3 more authors) (2012) Distribution of TAM relative to blood vessels in prostate carcinoma. Egyptian Journal of Pathology, 32 (2). pp. 217-226. ISSN 1687-4277
Colley, H.E., Hearnden, V., Jones, A.V. et al. (5 more authors) (2011) Development of tissue-engineered models of oral dysplasia and early invasive oral squamous cell carcinoma. British Journal of Cancer , 105 (10). pp. 1582-1592. ISSN 0007-0920
Smith, L.E., Hearnden, V. orcid.org/0000-0003-0838-7783, Lu, Z. et al. (6 more authors) (2011) Evaluating the use of optical coherence tomography for the detection of epithelial cancers in vitro. Journal of Biomedical Optics, 16 (11). 116015. ISSN 1083-3668
Yadev, N.R., Murdoch, C., Saville, S.P. et al. (1 more author) (2011) Evaluation of tissue engineered models of the oral mucosa to investigate oral candidiasis. Microbial Pathogenesis, 50 (6). pp. 278-285. ISSN 0882-4010
Khurram, S.A., Whawell, S.A., Bingle, L. et al. (3 more authors) (2010) Functional expression of the chemokine receptor XCR1 on oral epithelial cells. The Journal of Pathology, 221 (2). 153 - 163. ISSN 0022-3417
Proceedings Paper
Barragan Vazquez, I., Danby, S., Garcia Gonzalez, V.M. et al. (3 more authors) (2022) P39: Development of an in vitro immunocompetent human skin-equivalent model. In: British Journal of Dermatology. British Society for Investigative Dermatology Virtual Annual Meeting, 29-31 Mar 2021, Virtual. Wiley , E29-E29.
Harding, A., Danby, S., Murdoch, C. orcid.org/0000-0001-9724-122X et al. (2 more authors) (2022) P42: Development and validation of tissue-engineered human skin equivalents to detect stinging potential. In: British Journal of Dermatology. British Society for Investigative Dermatology Virtual Annual Meeting, 29-31 Mar 2021, Virtual. Wiley , E31-E31.
Colley, H.E. orcid.org/0000-0003-0053-7468, Said, Z., Santocildes-Romero, M.E. et al. (7 more authors) (2018) Novel bilayer mucoadhesive patches for delivery of clobetasol-17-propionate to the oral mucosa to treat oral lichen planus; an in vitro and in vivo evaluation. In: Oral Surgery Oral Medicine Oral Pathology and Oral Radiology. Annual Meeting of the American Academy of Oral Medicine, 10-14 Apr 2018, San Antonio, TX, USA. Elsevier , e204-e204.
Webb, S., Sharma, P., Colley, H.E. orcid.org/0000-0003-0053-7468 et al. (5 more authors) (2018) Defining skin xenobiotic metabolism using a combined in vitro/in silico approach. In: Applied In Vitro Toxicology. 2017 Annual Meeting of the UK In Vitro Toxicology Society (IVTS), 23-24 Nov 2017, London, UK. Mary Ann Liebert .
Hadley, L., Colley, H.E. orcid.org/0000-0003-0053-7468 and Murdoch, C. (2016) Development of macrophage-containing in vitro 3D models of oral cancer. In: Oral Diseases. 13th Biennial Congress of the European Association of Oral Medicine, 15-17 Sep 2016, Torino, Italy. Wiley , pp. 10-11.
Santocildes-Romero, M.E., Hadley, L., Clitherow, K.H. et al. (5 more authors) (2016) Novel electrospun bioadhesive oral patches for mucosal drug delivery. In: Oral Diseases. 13th Biennial Congress of the European Association of Oral Medicine, 15-17 Sep 2016, Torino, Italy. Wiley , p. 11.
Hadley, L., Santocildes-Romero, M.E., Thornhill, M.H. orcid.org/0000-0003-0681-4083 et al. (4 more authors) (2016) Pre-clinical evaluation of novel electrospun patches for intra-oral drug delivery. In: Oral Diseases. 13th Biennial Congress of the European Association of Oral Medicine, 15-17 Sep 2016, Torino, Italy. Wiley , pp. 10-13.
Colley, H.E. orcid.org/0000-0003-0053-7468, D'Apice, K., Baker, S.R. orcid.org/0000-0002-2861-451X et al. (5 more authors) (2016) Adhesion and acceptability of novel oral patches in human volunteers. In: Oral Diseases. 13th Biennial Congress of the European Association of Oral Medicine, 15-17 Sep 2016, Torino, Italy. Wiley , p. 19.
Grayson, A., Hearnden, V.L. orcid.org/0000-0003-0838-7783, Colley, H. et al. (3 more authors) (2016) Isolation and immortalisation of tonsillar keratinocytes for three-dimensional tissue engineered tonsil mucosal models. In: European Cells and Materials. Tissue Engineeering and Regenerative Medicine International Society, Uppsala 2016, 28 Jun - 01 Jul 2016, Uppsala, Sweden. AO Research Institute Davos , p. 20.