Items where authors include "Mead, R.J."

Article

Alix, J.J.P. orcid.org/0000-0001-8391-9749, Plesia, M., Dudgeon, A.P. orcid.org/0000-0002-4536-1147 et al. (9 more authors) (2024) Conformational fingerprinting with Raman spectroscopy reveals protein structure as a translational biomarker of muscle pathology. The Analyst. ISSN 0003-2654

Richardson, P.J. orcid.org/0000-0001-7813-041X, Smith, D.P., de Giorgio, A. et al. (6 more authors) (2023) Janus kinase inhibitors are potential therapeutics for amyotrophic lateral sclerosis. Translational Neurodegeneration, 12 (1). 47. ISSN 2047-9158

Alix, J.J.P. orcid.org/0000-0001-8391-9749, Plesia, M., Shaw, P.J. orcid.org/0000-0002-8925-2567 et al. (2 more authors) (2023) Combining electromyography and Raman spectroscopy: optical EMG. Muscle & Nerve. ISSN 0148-639X

Allen, S.P. orcid.org/0000-0003-4418-7375, Al Sultan, A., Kabucho Kibirige, E. et al. (13 more authors) (2023) A Y374X TDP43 truncation leads to an altered metabolic profile in amyotrophic lateral sclerosis fibroblasts driven by pyruvate and TCA cycle intermediate alterations. Frontiers in Aging Neuroscience, 15. 1151848. ISSN 1663-4365

Castelli, L.M., Lin, Y.-H., Sanchez-Martinez, A. et al. (19 more authors) (2023) A cell-penetrant peptide blocking C9ORF72-repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins. Science Translational Medicine, 15 (685). ISSN 1946-6234

Alix, J.J.P. orcid.org/0000-0001-8391-9749, Plesia, M., Schooling, C.N. et al. (9 more authors) (2022) Non‐negative matrix factorisation of Raman spectra finds common patterns relating to neuromuscular disease across differing equipment configurations, preclinical models and human tissue. Journal of Raman Spectroscopy. ISSN 0377-0486

Alix, J.J.P. orcid.org/0000-0001-8391-9749, Plesia, M., Hool, S.A. et al. (5 more authors) (2022) Fiber optic Raman spectroscopy for the evaluation of disease state in Duchenne muscular dystrophy: An assessment using the mdx model and human muscle. Muscle and Nerve, 66 (3). pp. 362-369. ISSN 0148-639X

Cooper‐Knock, J., Julian, T.H., Feneberg, E. et al. (15 more authors) (2022) Atypical TDP-43 protein expression in an ALS pedigree carrying a p.Y374X truncation mutation in TARDBP. Brain Pathology. e13104. ISSN 1015-6305

Kirby, A.J., Palmer, T., Mead, R.J. orcid.org/0000-0002-3207-0068 et al. (2 more authors) (2022) Caudal–rostral progression of alpha motoneuron degeneration in the SOD1G93A mouse model of amyotrophic lateral sclerosis. Antioxidants, 11 (5). 983.

Anton, A. orcid.org/0000-0002-1356-4513, Mead, R.J. orcid.org/0000-0002-3207-0068, Shaw, P.J. orcid.org/0000-0002-8925-2567 et al. (6 more authors) (2022) Assessment of the precision in measuring glutathione at 3 T with a MEGA-PRESS sequence in primary motor cortex and occipital cortex. Journal of Magnetic Resonance Imaging, 55 (2). pp. 435-442. ISSN 1053-1807

Roesl, C., Evans, E.R., Dissanayake, K.N. et al. (15 more authors) (2021) Confocal endomicroscopy of neuromuscular junctions stained with physiologically inert protein fragments of tetanus toxin. Biomolecules, 11 (10). 1499.

Jiménez-Villegas, J., Ferraiuolo, L. orcid.org/0000-0001-9118-5714, Mead, R.J. orcid.org/0000-0002-3207-0068 et al. (3 more authors) (2021) NRF2 as a therapeutic opportunity to impact in the molecular roadmap of ALS. Free Radical Biology and Medicine, 173. pp. 125-141. ISSN 0891-5849

Keerie, A., Brown-Wright, H., Kirkland, I. et al. (4 more authors) (2021) The GLP-1 receptor agonist, liraglutide, fails to slow disease progression in SOD1G93A and TDP-43Q331K transgenic mouse models of ALS. Scientific Reports, 11. 17027. ISSN 2045-2322

Watkins, J.A., Alix, J.J.P., Shaw, P.J. orcid.org/0000-0002-8925-2567 et al. (1 more author) (2021) Extensive phenotypic characterisation of a human TDP-43^Q331K transgenic mouse model of amyotrophic lateral sclerosis (ALS). Scientific Reports, 11 (1). 16659.

Ciervo, Y., Gatto, N., Allen, C. et al. (4 more authors) (2021) Adipose-derived stem cells protect motor neurons and reduce glial activation in both in vitro and in vivo models of ALS. Molecular Therapy — Methods & Clinical Development, 21. pp. 413-433. ISSN 2329-0501

Pham, T.K., Buczek, W.A., Mead, R.J. orcid.org/0000-0002-3207-0068 et al. (2 more authors) (2021) Proteomic approaches to study cysteine oxidation: applications in neurodegenerative diseases. Frontiers in Molecular Neuroscience, 14. 678837. ISSN 1662-5099

Plesia, M., Stevens, O.A., Lloyd, G.R. et al. (8 more authors) (2021) In vivo fiber optic raman spectroscopy of muscle in preclinical models of amyotrophic lateral sclerosis and Duchenne muscular dystrophy. ACS Chemical Neuroscience, 12 (10). pp. 1768-1776. ISSN 1948-7193

Watkins, J., Ghosh, A., Keerie, A.F.A. et al. (3 more authors) (2020) Female sex mitigates motor and behavioural phenotypes in TDP-43Q331K knock-in mice. Scientific Reports, 10 (1). 19220.

Ciervo, Y., Ning, K orcid.org/0000-0002-0771-1134, Jun, X. et al. (2 more authors) (2017) Advances, challenges and future directions for stem cell therapy in amyotrophic lateral sclerosis. Molecular Neurodegeneration, 12. 85. ISSN 1750-1326

Bennett, E.J., Mead, R.J., Azzouz, M. et al. (2 more authors) (2014) Early Detection of Motor Dysfunction in the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis (ALS) Using Home Cage Running Wheels. PLOS ONE, 9 (9). e107918. ISSN 1932-6203