Items where authors include "Hughes, TA"

Article

Dutta, R, Bhattacharya, E, Pramanik, A orcid.org/0000-0002-5827-6267 et al. (2 more authors) (2022) Potent nutraceuticals having antioxidant, DNA damage protecting potential and anti-cancer properties from the leaves of four Ficus species. Biocatalysis and Agricultural Biotechnology, 44. 102461. p. 102461. ISSN 1878-8181

Pramanik, A orcid.org/0000-0002-5827-6267, Xu, Z, Shamsuddin, SH et al. (9 more authors) (2022) Affimer Tagged Cubosomes: Targeting of Carcinoembryonic Antigen Expressing Colorectal Cancer Cells Using In Vitro and In Vivo Models. ACS Applied Materials and Interfaces, 14 (9). pp. 11078-11091. ISSN 1944-8244

Websdale, A, Kiew, Y, Chalmers, P et al. (11 more authors) (2022) Pharmacologic and genetic inhibition of cholesterol esterification enzymes reduces tumour burden: a systematic review and meta-analysis of preclinical models. Biochemical pharmacology, 196. 114731. ISSN 0006-2952

Baxter, DE, Allinson, LM, Al Amri, WS et al. (5 more authors) (2021) MiR-195 and Its Target SEMA6D Regulate Chemoresponse in Breast Cancer. Cancers, 13 (23). 5979. ISSN 2072-6694

Armstrong, GR, Khot, MI orcid.org/0000-0002-5062-2284, Portal, C et al. (7 more authors) (2021) A novel fluorescent c-met targeted imaging agent for intra-operative colonic tumour mapping: Translation from the laboratory into a clinical trial. Surgical Oncology. ISSN 0960-7404

Lianto, P, Hutchinson, SA, Moore, JB orcid.org/0000-0003-4750-1550 et al. (2 more authors) (2021) Characterization and prognostic value of LXR splice variants in triple-negative breast cancer. iScience, 24 (10). 103212. ISSN 2589-0042

Gwili, N, Jones, SJ, Al Amri, W et al. (15 more authors) (2021) Transcriptome profiles of stem-like cells from primary breast cancers allow identification of ITGA7 as a predictive marker of chemotherapy response. British Journal of Cancer, 125. pp. 983-993. ISSN 0007-0920

Hsu, SN, Hui, EWE, Liu, M et al. (3 more authors) (2021) Revealing nuclear receptor hub modules from Basal-like breast cancer expression networks. PLoS One, 16 (6). e0252901. ISSN 1932-6203

Stevens, W, Farrow, IM, Georgiou, L et al. (9 more authors) (2021) Breast tumour volume and blood flow measured by MRI after one cycle of epirubicin and cyclophosphamide-based neoadjuvant chemotherapy as predictors of pathological response. The British Journal of Radiology. 20201396-. ISSN 0007-1285

Armstrong, GR, Khot, MI orcid.org/0000-0002-5062-2284, Tiernan, JP et al. (5 more authors) (2021) The utility of c-Met as a diagnostic tissue biomarker in primary colorectal cancer. International Journal of Experimental Pathology, 102 (3). pp. 172-178. ISSN 0959-9673

Bose, R, Bhattacharya, E, Pramanik, A orcid.org/0000-0002-5827-6267 et al. (2 more authors) (2021) Potential oil resources from underutilized seeds of Sterculia foetida, L. - Quality assessment and chemical profiling with other edible vegetable oils based on fatty acid composition, oxidative stability, antioxidant activity and cytotoxicity. Biocatalysis and Agricultural Biotechnology, 33. 102002. ISSN 1878-8181

Hutchinson, SA, Websdale, A, Cioccoloni, G orcid.org/0000-0003-0102-9182 et al. (15 more authors) (2021) Liver x receptor alpha drives chemoresistance in response to side-chain hydroxycholesterols in triple negative breast cancer. Oncogene, 40. pp. 2872-2883. ISSN 0950-9232

Broad, RV, Jones, SJ, Teske, MC et al. (4 more authors) (2021) Inhibition of interferon-signalling halts cancer-associated fibroblast-dependent protection of breast cancer cells from chemotherapy. British Journal of Cancer, 124. pp. 1110-1120. ISSN 0007-0920

Al Amri, WS, Baxter, DE, Hanby, AM orcid.org/0000-0001-7966-1570 et al. (4 more authors) (2020) Identification of candidate mediators of chemoresponse in breast cancer through therapy-driven selection of somatic variants. Breast Cancer Research and Treatment, 183 (3). pp. 607-616. ISSN 0167-6806

Verma, R, Hanby, AM orcid.org/0000-0001-7966-1570, Horgan, K et al. (4 more authors) (2020) Levels of different subtypes of tumour-infiltrating lymphocytes correlate with each other, with matched circulating lymphocytes, and with survival in breast cancer. Breast Cancer Research and Treatment, 183 (1). pp. 49-59. ISSN 0167-6806

Hitchcock, J orcid.org/0000-0003-2226-6734, White, AL, Hondow, N orcid.org/0000-0001-9368-2538 et al. (4 more authors) (2020) Metal-shell nanocapsules for the delivery of cancer drugs. Journal of Colloid and Interface Science, 567. pp. 171-180. ISSN 0021-9797

Al Amri, WS, Allinson, LM, Baxter, DE orcid.org/0000-0001-8830-6802 et al. (7 more authors) (2020) Genomic and expression analyses define MUC17 and PCNX1 as predictors of chemotherapy response in breast cancer. Molecular Cancer Therapeutics, 19 (3). pp. 945-955. ISSN 1535-7163

Hutchinson, SA, Lianto, P, Roberg-Larsen, H et al. (3 more authors) (2019) ER-Negative Breast Cancer Is Highly Responsive to Cholesterol Metabolite Signalling. Nutrients, 11 (11). 2618. ISSN 2072-6643

Chatterjee, A, Jana, S, Chatterjee, S et al. (6 more authors) (2019) MicroRNA-222 reprogrammed cancer-associated fibroblasts enhance growth and metastasis of breast cancer. British Journal of Cancer, 121. pp. 679-689. ISSN 0007-0920

Hutchinson, SA, Lianto, P, Moore, JB orcid.org/0000-0003-4750-1550 et al. (2 more authors) (2019) Phytosterols Inhibit Side-Chain Oxysterol Mediated Activation of LXR in Breast Cancer Cells. International Journal of Molecular Sciences, 20 (13). 3241. ISSN 1661-6596

Baxter, DE orcid.org/0000-0001-8830-6802, Kim, B, Hanby, AM orcid.org/0000-0001-7966-1570 et al. (3 more authors) (2018) Neoadjuvant Endocrine Therapy in Breast Cancer Upregulates the Cytotoxic Drug Pump ABCG2/BCRP, and May Lead to Resistance to Subsequent Chemotherapy. Clinical Breast Cancer, 18 (6). pp. 481-488. ISSN 1526-8209

Thorne, JL orcid.org/0000-0002-3037-8528, Battaglia, S, Baxter, DE orcid.org/0000-0001-8830-6802 et al. (8 more authors) (2018) MiR-19b non-canonical binding is directed by HuR and confers chemosensitivity through regulation of P-glycoprotein in breast cancer. BBA - Gene Regulatory Mechanisms, 1861 (11). pp. 996-1006. ISSN 1874-9399

Khot, MI, Perry, SL orcid.org/0000-0002-2561-8195, Maisey, T et al. (5 more authors) (2018) Inhibiting ABCG2 could potentially enhance the efficacy of hypericin-mediated photodynamic therapy in spheroidal cell models of colorectal cancer. Photodiagnosis and Photodynamic Therapy, 23. pp. 221-229. ISSN 1572-1000

Pollard, J, Burns, PA, Hughes, TA orcid.org/0000-0003-1169-3386 et al. (7 more authors) (2018) Differential Expression of MicroRNAs in Breast Cancers from Four Different Ethnicities. Pathobiology, 85 (4). pp. 220-226. ISSN 1015-2008

Baldacchino, S, Wastall, LM, Saliba, C et al. (6 more authors) (2017) CIP2A expression predicts recurrences of tamoxifen-treated breast cancer. Tumour Biology, 39 (10). ISSN 1010-4283

Millican-Slater, RA, Sayers, CD, Hanby, AM et al. (1 more author) (2016) Expression of phosphorylated eIF4E-binding protein 1, but not of eIF4E itself, predicts survival in male breast cancer. British Journal of Cancer, 115 (3). pp. 339-345. ISSN 0007-0920

Verma, R, Foster, RE, Horgan, K et al. (5 more authors) (2016) Lymphocyte depletion and repopulation after chemotherapy for primary breast cancer. Breast Cancer Research, 18. 10. ISSN 1465-5411

Smith, L, Baxter, EW, Chambers, PA et al. (8 more authors) (2015) Down-Regulation of miR-92 in Breast Epithelial Cells and in Normal but Not Tumour Fibroblasts Contributes to Breast Carcinogenesis. PLoS ONE, 10 (10). e0139698. ISSN 1932-6203

Kim, B, Stephen, SL, Hanby, AM et al. (9 more authors) (2015) Chemotherapy induces Notch1-dependent MRP1 up-regulation, inhibition of which sensitizes breast cancer cells to chemotherapy. BMC Cancer, 15. 634. ISSN 1471-2407

Hayes, J, Thygesen, H, Tumilson, C et al. (8 more authors) (2015) Prediction of clinical outcome in glioblastoma using a biologically relevant nine-microRNA signature. Molecular Oncology, 9 (3). 704 - 714. ISSN 1574-7891

Tiernan, JP, Ingram, N, Marston, G et al. (6 more authors) (2015) CEA-targeted nanoparticles allow specific in vivo fluorescent imaging of colorectal cancer models. Nanomedicine. 1 - 9. ISSN 1743-5889

Hayes, J, Thygesen, H, Droop, A et al. (5 more authors) (2014) Prognostic microRNAs in high-grade glioma reveal a link to oligodendrocyte precursor differentiation. Oncoscience, 2 (3). 252 - 262.

Langlands, FE, Dodwell, D, Hanby, AM et al. (6 more authors) (2014) PSMD9 expression predicts radiotherapy response in breast cancer. Molecular Cancer, 13. 73. ISSN 1476-4598

Verghese, ET, Drury, R, Green, CA et al. (10 more authors) (2013) MiR-26b is down-regulated in carcinoma-associated fibroblasts from ER-positive breast cancers leading to enhanced cell migration and invasion. The Journal of Pathology, 231 (3). pp. 388-399. ISSN 0022-3417

Tiernan, JP, Perry, SL, Verghese, ET et al. (4 more authors) (2013) Carcinoembryonic antigen is the preferred biomarker for in vivo colorectal cancer targeting. British Journal of Cancer, 108 (3). 662 - 667. ISSN 0007-0920

Shaaban, AM, Green, AR, Karthik, S et al. (9 more authors) (2008) Nuclear and Cytoplasmic Expression of ER 1, ER 2, and ER 5 Identifies Distinct Prognostic Outcome for Breast Cancer Patients. Clinical Cancer Research, 14 (16). pp. 5228-5235. ISSN 1078-0432

Conference or Workshop Item

Websdale, A, Chalmers, P, Chen, X et al. (9 more authors) (2021) Cholesterol esterification enzymes promote cancer growth and are potential therapeutic targets for repurposed drugs: a systematic review and meta-analysis of pre-clinical evidence. In: The Nutrition Society Summer Conference: Nutrition in a changing world, 06-08 Jul 2021, Online.

Cioccoloni, G orcid.org/0000-0003-0102-9182, Websdale, A, Soteriou, C et al. (8 more authors) (2021) Overlap between nutrient metabolism and chemotherapy detoxification in triple negative breast cancer. In: The Nutrition Society Summer Conference: Nutrition in a changing world, 06-08 Jul 2021, Online.

Lianto, P, Hughes, TA orcid.org/0000-0003-1169-3386, Moore, BJ et al. (1 more author) (2020) Splicing of the cholesterol homeostasis protein LXR is a prognostic indicator for triple negative breast cancer patients. In: Nutrition Society Live 2020, 14-15 Jul 2020, Online.

Proceedings Paper

Websdale, A, Hutchinson, SA, Lianto, P et al. (7 more authors) (2020) Cholesterol side-chain hydroxylation is associated with expression of P-glycoprotein and disease-free survival in triple negative breast cancer patients. In: Proceedings of the Nutrition Society. Nutrition Society Live 2020, 14-15 Jul 2020, Online. Cambridge University Press .

Thorne, JL orcid.org/0000-0002-3037-8528, Battaglia, S, Jana, SS et al. (4 more authors) (2016) P-glycoprotein (ABCB1) expression during breast cancer development is regulated by HuR-dependent loading of miR-19b at non-canonical sites. In: Breast Cancer Research and Treatment. UK Breast Cancer Research Symposium 2016, 22-23 Jul 2016, London, UK. Springer , p. 188.