Items where authors include "Houlston, RS"

Article

Panopoulou, A, Cairns, DA orcid.org/0000-0002-2338-0179, Holroyd, AE et al. (13 more authors) (2022) Optimizing the value of lenalidomide maintenance by genetic profiling - an analysis of 556 Myeloma XI trial patients. Blood. ISSN 0006-4971

Chen, H, Majumdar, A, Wang, L et al. (75 more authors) (2021) Large-scale cross-cancer fine-mapping of the 5p15.33 region reveals multiple independent signals. HGG advances, 2 (3). 100041. ISSN 2666-2477

Croft, J, Ellis, S, Sherborne, AL et al. (19 more authors) (2021) Copy number evolution and its relationship with patient outcome—an analysis of 178 matched presentation-relapse tumor pairs from the Myeloma XI trial. Leukemia, 35 (7). pp. 2043-2053. ISSN 0887-6924

Shah, V, Sherborne, AL, Johnson, DC et al. (16 more authors) (2020) Predicting ultrahigh risk multiple myeloma by molecular profiling: an analysis of newly diagnosed transplant eligible myeloma XI trial patients. Leukemia, 34. pp. 3091-3096. ISSN 0887-6924

Hoang, PH, Cornish, AJ, Sherborne, AL et al. (8 more authors) (2020) An enhanced genetic model of relapsed IGH-translocated multiple myeloma evolutionary dynamics. Blood Cancer Journal, 10 (10). 101. ISSN 2044-5385

Zhu, Y, Wei, Y, Zhang, R et al. (74 more authors) (2019) Elevated platelet count appears to be causally associated with increased risk of lung cancer: A mendelian randomization analysis. Cancer Epidemiology, Biomarkers and Prevention, 28 (5). pp. 935-942. ISSN 1055-9965

Johansson, M, Carreras-Torres, R, Scelo, G et al. (110 more authors) (2019) The influence of obesity-related factors in the etiology of renal cell carcinoma—A mendelian randomization study. PLoS Medicine, 16 (1). e1002724. ISSN 1549-1277

Went, M, Sud, A, Speedy, H et al. (52 more authors) (2018) Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology. Blood Cancer Journal, 9. ARTN 1. ISSN 2044-5385

Shah, V, Johnson, DC, Sherborne, AL et al. (19 more authors) (2018) Subclonal TP53 copy number is associated with prognosis in multiple myeloma. Blood, 132 (23). pp. 2465-2469. ISSN 0006-4971

Litchfield, K, Loveday, C, Levy, M et al. (9 more authors) (2018) Large-scale Sequencing of Testicular Germ Cell Tumour (TGCT) Cases Excludes Major TGCT Predisposition Gene. European Urology, 73 (6). pp. 828-831. ISSN 0302-2838

Vijayakrishnan, J, Studd, J, Broderick, P et al. (37 more authors) (2018) Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia. Nature Communications, 9 (1). 1340. ISSN 2041-1723

Machiela, MJ, Hofmann, JN, Carreras-Torres, R et al. (109 more authors) (2017) Genetic variants related to longer telomere length are associated with increased risk of renal cell carcinoma. European Urology, 72 (5). pp. 747-754. ISSN 0302-2838

Johnson, DC, Lenive, O, Mitchell, J et al. (14 more authors) (2017) Neutral tumor evolution in myeloma is associated with poor prognosis. Blood, 130 (14). pp. 1639-1643. ISSN 0006-4971

Litchfield, K, Levy, M, Orlando, G et al. (30 more authors) (2017) Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor. Nature Genetics, 49 (7). pp. 1133-1140. ISSN 1061-4036

Scelo, G, Purdue, MP, Brown, KM et al. (120 more authors) (2017) Genome-wide association study identifies multiple risk loci for renal cell carcinoma. Nature Communications, 8. 15724. ISSN 2041-1723

Shah, V, Sherborne, AL, Walker, BA et al. (19 more authors) (2017) Prediction of outcome in newly diagnosed myeloma: a meta-analysis of the molecular profiles of 1,905 trial patients. Leukemia, 32. pp. 102-110. ISSN 0887-6924

Vijayakrishnan, J, Kumar, R, Henrion, MYR et al. (26 more authors) (2017) A genome-wide association study identifies risk loci for childhood acute lymphoblastic leukemia at 10q26.13 and 12q23.1. Leukemia, 31 (3). pp. 573-579. ISSN 0887-6924

Litchfield, K, Levy, M, Dudakia, D et al. (13 more authors) (2016) Rare disruptive mutations in ciliary function genes contribute to testicular cancer susceptibility. Nature Communications, 7. 13840. ISSN 2041-1723

Mitchell, JS, Li, N, Weinhold, N et al. (55 more authors) (2016) Genome-wide association study identifies multiple susceptibility loci for multiple myeloma. Nature Communications, 7. 12050.

Chubb, D, Broderick, P, Dobbins, SE et al. (12 more authors) (2016) Rare disruptive mutations and their contribution to the heritable risk of colorectal cancer. Nature Communications, 7. 11883. ISSN 2041-1723

Kinnersley, B, Kamatani, Y, Labussiere, M et al. (16 more authors) (2016) Search for new loci and low-frequency variants influencing glioma risk by exome-array analysis. European Journal of Human Genetics, 24 (5). pp. 717-724. ISSN 1018-4813

Johnson, DC, Weinhold, N, Mitchell, J et al. (18 more authors) (2016) Genetic factors influencing the risk of multiple myeloma bone disease. Leukemia, 30 (4). pp. 883-888. ISSN 0887-6924

Johnson, DC, Weinhold, N, Mitchell, JS et al. (19 more authors) (2016) Genome-wide association study identifies variation at 6q25.1 associated with survival in multiple myeloma. Nature Communications, 7. 10290.

Timofeeva, MN, Kinnersley, B, Farrington, SM et al. (58 more authors) (2015) Recurrent Coding Sequence Variation Explains Only A Small Fraction of the Genetic Architecture of Colorectal Cancer. Scientific Reports, 5. 16286. ISSN 2045-2322

Litchfield, K, Holroyd, A, Lloyd, A et al. (14 more authors) (2015) Identification of four new susceptibility loci for testicular germ cell tumour. Nature Communications, 6. 8690. ISSN 2041-1723

Vijayakrishnan, J, Henrion, M, Moorman, AV et al. (24 more authors) (2015) The 9p21.3 risk of childhood acute lymphoblastic leukaemia is explained by a rare high-impact variant in CDKN2A. Scientific Reports, 5. 15065. ISSN 2045-2322

Kinnersley, B, Labussière, M, Holroyd, A et al. (20 more authors) (2015) Genome-wide association study identifies multiple susceptibility loci for glioma. Nature Communications, 6. ARTN 8559. p. 8559. ISSN 2041-1723

Mitchell, JS, Johnson, DC, Litchfield, K et al. (8 more authors) (2015) Implementation of genome-wide complex trait analysis to quantify the heritability in multiple myeloma. Scientific Reports, 5. 12473. ISSN 2045-2322

Freitag, DF, Butterworth, AS, Willeit, P et al. (150 more authors) (2015) Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: a Mendelian randomisation analysis. Lancet Diabetes and Endocrinology, 3 (4). pp. 243-253. ISSN 2213-8587

Morris, EJA, Penegar, S, Whiffin, N et al. (6 more authors) (2015) A retrospective observational study of the relationship between single nucleotide polymorphisms associated with the risk of developing Colorectal cancer and survival. PLoS One, 10 (2). e0117816. e0117816 - ?. ISSN 1932-6203

Palles, C, Cazier, J-B, Howarth, KM et al. (36 more authors) (2013) Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas. Nature Genetics, 45 (2). pp. 136-144. ISSN 1061-4036

Conference or Workshop Item

Lindstrom, S, Kar, S, Wang, L et al. (25 more authors) (2020) Cross-cancer GWAS meta-analysis of more than 370,000 cases and 530,000 controls identifies multiple novel cancer risk regions. In: AACR Annual Meeting 2020, 27 Apr - 24 Jun 2020, Philadelphia, PA, USA.

Feng, H, Majumdar, A, Pasaniuc, B et al. (20 more authors) (2020) Cross-cancer cross-tissue Transcriptome-wide Association Study (TWAS) of 11 cancers identifies 56 novel genes. In: AACR Annual Meeting 2020, 27 Apr 2020, Philadelphia, PA, USA.

Proceedings Paper

Shah, V, Johnson, DC, Sherborne, AL et al. (18 more authors) (2018) Characterisation of Long-Term Responders to First-Line Myeloma Therapy - Results from the UK Myeloma IX and XI Trials. In: Blood. 60th ASH Annual Meeting, 01-04 Dec 2018, San Diego, California, USA. American Society of Hematology , p. 2000.