Items where authors include "Firth, James D."

Article

Jones, S. Paul, Firth, James D., Wheldon, Mary C. et al. (11 more authors) (2022) Exploration of piperidine 3D fragment chemical space : synthesis and 3D shape analysis of fragments derived from 20 regio- and diastereoisomers of methyl substituted pipecolinates. RSC Medicinal Chemistry. pp. 1614-1620. ISSN 2632-8682

Gomez-Angel, Andres R., Donald, James R. orcid.org/0000-0002-2176-4902, Firth, James D. et al. (4 more authors) (2021) Synthesis and functionalisation of a bifunctional normorphan 3D building block for medicinal chemistry. Tetrahedron. 131961. ISSN 0040-4020

Kwong, Alice, Firth, James D., Farmer, Thomas J. orcid.org/0000-0002-1039-7684 et al. (1 more author) (2021) Rapid “high” temperature batch and flow lithiation-trapping of N-Boc pyrrolidine. Tetrahedron. 131899. ISSN 0040-4020

Makraki, Eleni, Darby, John F. orcid.org/0000-0003-2754-6348, Carneiro, Marta G. et al. (6 more authors) (2020) Fragment-derived modulators of an industrial β-glucosidase. The Biochemical journal. pp. 4383-4395. ISSN 1470-8728

Douangamath, Alice, Fearon, Daren, Gehrtz, Paul et al. (31 more authors) (2020) Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease. Nature Communications. 5047. ISSN 2041-1723

Darby, John F. orcid.org/0000-0003-2754-6348, Atobe, Masakazu, Firth, James D. et al. (4 more authors) (2017) Increase of enzyme activity through specific covalent modification with fragments. Chemical Science. pp. 7772-7779. ISSN 2041-6539