Items where authors include "Cork, M.J."
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Paller, A.S., Siegfried, E.C., Cork, M.J. orcid.org/0000-0003-4428-2428 et al. (7 more authors) (2024) Infections in children aged 6 months to 5 years treated with dupilumab in a placebo-controlled clinical trial of moderate-to-severe atopic dermatitis. Pediatric Drugs. ISSN 1174-5878
Andrew, P.V. orcid.org/0000-0002-9763-6413, Pinnock, A., Poyner, A. et al. (5 more authors) (2024) Maintenance of an acidic skin surface with a novel zinc lactobionate emollient preparation improves skin barrier function in patients with atopic dermatitis. Dermatology and Therapy. ISSN 2193-8210
Simpson, E.L., Blauvelt, A., Silverberg, J.I. et al. (5 more authors) (2024) Tralokinumab provides clinically meaningful responses at week 16 in adults with moderate-to-severe atopic dermatitis who do not achieve IGA 0/1. American Journal of Clinical Dermatology, 25. pp. 139-148. ISSN 1175-0561
Cork, M.J. orcid.org/0000-0003-4428-2428, Lockshin, B., Pinter, A. et al. (3 more authors) (2024) Clinically meaningful responses to dupilumab among children aged 6 months to 5 years with moderate-to-severe atopic dermatitis who did not achieve clear or almost clear skin according to the investigator’s global assessment: a post hoc analysis of a phase 3 trial. Acta Dermato-Venereologica, 104. 13467. ISSN 0001-5555
Flohr, C., Cork, M.J. orcid.org/0000-0003-4428-2428, Ardern-Jones, M.R. et al. (6 more authors) (2023) Efficacy and safety of abrocitinib monotherapy in adolescents and adults: a post hoc analysis of the phase 3 JAK1 atopic dermatitis efficacy and safety (JADE) REGIMEN clinical trial. Journal of Dermatological Treatment, 34 (1). 2200866. ISSN 0954-6634
Williams, S.F. orcid.org/0000-0002-1296-0098, Wan, H., Chittock, J. orcid.org/0000-0002-1595-7441 et al. (4 more authors) (2023) Characterization of skin barrier defects using infrared spectroscopy in patients with atopic dermatitis. Clinical and Experimental Dermatology. ISSN 0307-6938
Chittock, J. orcid.org/0000-0002-1595-7441, Kay, L., Brown, K. et al. (4 more authors) (2023) Association between skin barrier development and early-onset atopic dermatitis: a longitudinal birth cohort study. Journal of Allergy and Clinical Immunology. ISSN 0091-6749
Cork, M.J., Thaçi, D., Eichenfield, L.F. et al. (8 more authors) (2023) Dupilumab safety and efficacy in a phase III open-label extension trial in children 6–11 years of age with severe atopic dermatitis. Dermatology and Therapy, 13. pp. 2697-2719. ISSN 2193-8210
Weidinger, S., Bieber, T., Cork, M.J. orcid.org/0000-0003-4428-2428 et al. (8 more authors) (2023) Safety and efficacy of amlitelimab, a fully human nondepleting, noncytotoxic anti-OX40 ligand monoclonal antibody, in atopic dermatitis: results of a phase IIa randomized placebo-controlled trial. British Journal of Dermatology, 189 (5). pp. 531-539. ISSN 0007-0963
Flohr, C. orcid.org/0000-0003-4884-6286, Rosala-Hallas, A., Jones, A.P. et al. (76 more authors) (2023) Efficacy and safety of ciclosporin versus methotrexate in the treatment of severe atopic dermatitis in children and young people (TREAT): a multicentre parallel group assessor-blinded clinical trial. British Journal of Dermatology. ljad281. ISSN 0007-0963
Siegfried, E.C., Simpson, E.L. orcid.org/0000-0001-7353-5979, Cork, M.J. et al. (7 more authors) (2023) Dupilumab Treatment Leads to Rapid and Consistent Improvement of Atopic Dermatitis in All Anatomical Regions in Patients Aged 6 Months to 5 Years. Dermatology and Therapy, 13 (9). pp. 1987-2000. ISSN 2193-8210
Siegfried, E.C., Cork, M.J., Katoh, N. et al. (6 more authors) (2023) Dupilumab provides clinically meaningful responses in children aged 6–11 years with severe atopic dermatitis: post hoc analysis results from a phase III trial. American Journal of Clinical Dermatology, 24 (5). pp. 787-798. ISSN 1175-0561
Sach, T.H. orcid.org/0000-0002-8098-9220, Lartey, S.T., Davies, C. et al. (20 more authors) (2023) Emollients for preventing atopic eczema: cost‐effectiveness analysis of the BEEP trial. Clinical & Experimental Allergy. ISSN 0954-7894
Flohr, C. orcid.org/0000-0003-4884-6286, Irvine, A.D. orcid.org/0000-0002-9048-2044, Cork, M.J. orcid.org/0000-0003-4428-2428 et al. (6 more authors) (2023) Dupilumab improves patient-reported symptoms and health-related quality of life in children aged 6–11 years with severe atopic dermatitis. British Journal of Dermatology, 189 (2). pp. 238-240. ISSN 0007-0963
Bieber, T. orcid.org/0000-0002-8800-3817, Thyssen, J.P. orcid.org/0000-0003-3770-1743, Irvine, A.D. orcid.org/0000-0002-9048-2044 et al. (6 more authors) (2023) Early improvements in signs and symptoms predict clinical response to baricitinib in patients with moderate-to-severe atopic dermatitis. Clinical and Experimental Dermatology, 48 (8). pp. 881-888. ISSN 0307-6938
Simpson, E.L., Silverberg, J.I., Thyssen, J.P. et al. (10 more authors) (2023) Efficacy and safety of abrocitinib in patients with severe and/or difficult-to-treat atopic dermatitis: a post hoc analysis of the randomized phase 3 JADE COMPARE trial. American Journal of Clinical Dermatology, 24. pp. 609-621. ISSN 1175-0561
Paller, A.S. orcid.org/0000-0001-6187-6549, Siegfried, E.C., Cork, M.J. orcid.org/0000-0003-4428-2428 et al. (8 more authors) (2023) Laboratory safety from a randomized 16-week phase III study of dupilumab in children aged 6 months to 5 years with moderate-to-severe atopic dermatitis. Pediatric Drugs, 25. pp. 67-77. ISSN 1174-5878
Chittock, J. orcid.org/0000-0002-1595-7441, Cork, M.J. orcid.org/0000-0003-4428-2428 and Danby, S.G. orcid.org/0000-0001-7363-140X (2022) REAL-TIME INFRARED Spectroscopic measurement of natural moisturising factor. Journal of Investigative Dermatology. ISSN 0022-202X
Bradshaw, L.E., Wyatt, L.A., Brown, S.J. et al. (22 more authors) (2022) Emollients for prevention of atopic dermatitis; 5‐year findings from the BEEP randomised trial. Allergy. ISSN 1398-9995
Beck, L.A., Cork, M.J. orcid.org/0000-0003-4428-2428, Amagai, M. et al. (4 more authors) (2022) Type 2 inflammation contributes to skin barrier dysfunction in atopic dermatitis. JID Innovations, 2 (5). 100131. ISSN 2667-0267
Danby, S.G. orcid.org/0000-0001-7363-140X, Andrew, P.V., Taylor, R.N. et al. (8 more authors) (2022) Different types of emollient cream exhibit diverse physiological effects on the skin barrier in adults with atopic dermatitis. Clinical and Experimental Dermatology, 47 (6). pp. 1154-1164. ISSN 0307-6938
Danby, S.G. orcid.org/0000-0001-7363-140X, Andrew, P.V., Kay, L.J. et al. (5 more authors) (2022) Enhancement of stratum corneum lipid structure improves skin barrier function and protects against irritation in adults with dry, eczema‐prone, skin. British Journal of Dermatology, 186 (5). pp. 875-886. ISSN 0007-0963
Blauvelt, A., Guttman-Yassky, E., Paller, A.S. et al. (13 more authors) (2022) Long-term efficacy and safety of dupilumab in adolescents with moderate-to-severe atopic dermatitis : results through week 52 from a phase III open-label extension trial (LIBERTY AD PED-OLE). American Journal of Clinical Dermatology, 23 (3). pp. 365-383. ISSN 1175-0561
Paller, A.S., Beck, L.A., Blauvelt, A. et al. (9 more authors) (2022) Infections in children and adolescents treated with dupilumab in pediatric clinical trials for atopic dermatitis—a pooled analysis of trial data. Pediatric Dermatology, 39 (2). pp. 187-196. ISSN 0736-8046
Jabbar‐Lopez, Z.K., Ezzamouri, B., Briley, A. et al. (11 more authors) (2022) Randomized controlled pilot trial with ion‐exchange water softeners to prevent eczema (SOFTER trial). Clinical & Experimental Allergy, 52 (3). pp. 405-415. ISSN 0954-7894
Cork, M.J. orcid.org/0000-0003-4428-2428, McMichael, A., Teng, J. et al. (6 more authors) (2022) Impact of oral abrocitinib on signs, symptoms and quality of life among adolescents with moderate‐to‐severe atopic dermatitis : an analysis of patient‐reported outcomes. Journal of the European Academy of Dermatology and Venereology, 36 (3). pp. 422-433. ISSN 0926-9959
Danby, S.G. orcid.org/0000-0001-7363-140X, Draelos, Z.D., Gold, L.F.S. et al. (6 more authors) (2022) Vehicles for atopic dermatitis therapies: more than just a placebo. Journal of Dermatological Treatment, 33 (2). pp. 685-698. ISSN 0954-6634
Danby, S.G. orcid.org/0000-0001-7363-140X, Andrew, P.V., Brown, K. et al. (3 more authors) (2021) Response to: Letter to the Editor Regarding “An Investigation of the Skin Barrier Restoring Effects of a Cream and Lotion Containing Ceramides in a Multi-Vesicular Emulsion in People with Dry, Eczema-Prone, Skin: The RESTORE Study Phase 1”. Dermatology and Therapy, 11 (6). pp. 2249-2252. ISSN 2193-8210
Simpson, E.L., Paller, A.S., Siegfried, E.C. et al. (10 more authors) (2021) Dupilumab demonstrates rapid and consistent improvement in extent and signs of atopic dermatitis across all anatomical regions in pediatric patients 6 years of age and older. Dermatology and Therapy, 11. pp. 1643-1656. ISSN 2193-8210
Silverberg, J.I., Simpson, E.L., Guttman-Yassky, E. et al. (15 more authors) (2021) Dupilumab significantly modulates pain and discomfort in patients with atopic dermatitis : a post hoc analysis of 5 randomized clinical trials. Dermatitis, 32 (1S). S81-S91. ISSN 1710-3568
Paller, A.S., Wollenberg, A., Siegfried, E. et al. (12 more authors) (2021) Laboratory safety of dupilumab in patients aged 6–11 years with severe atopic dermatitis : results from a phase III clinical trial. Pediatric Drugs, 23 (5). pp. 515-527. ISSN 1174-5878
Stamatas, G.N., Bensaci, J., Greugny, E. et al. (6 more authors) (2021) A predictive self-organizing multicellular computational model of infant skin permeability to topically applied substances. Journal of Investigative Dermatology, 141 (8). 2049-2055.e1. ISSN 0022-202X
Lin, W.C. orcid.org/0000-0002-1261-3125, Byers, R.A. orcid.org/0000-0001-8582-9325, Li, W. et al. (3 more authors) (2021) Imaging striae distensae : a comparison between PS-OCT and digital dermoscopy. Biomedical Optics Express, 12 (6). pp. 3296-3311.
Cork, M.J. orcid.org/0000-0003-4428-2428, Thaçi, D., Eichenfield, L.F. et al. (12 more authors) (2021) Dupilumab provides favourable long‐term safety and efficacy in children aged ≥ 6 to < 12 years with uncontrolled, severe atopic dermatitis: results from an open‐label phase IIa study and subsequent phase III open‐label extension study. British Journal of Dermatology, 184 (5). pp. 857-870. ISSN 0007-0963
Thyssen, J.P., Vestergaard, C., Barbarot, S. et al. (32 more authors) (2021) European Task Force on Atopic Dermatitis (ETFAD): position on vaccination of adult patients with atopic dermatitis against COVID‐19 (SARS‐CoV‐2) being treated with systemic medication and biologics. Journal of the European Academy of Dermatology and Venereology, 35 (5). e308-e311. ISSN 0926-9959
Wollenberg, A., Blauvelt, A., Guttman‐Yassky, E. et al. (19 more authors) (2021) Tralokinumab for moderate‐to‐severe atopic dermatitis: results from two 52‐week, randomized, double‐blind, multicentre, placebo‐controlled phase III trials (ECZTRA 1 and ECZTRA 2). British Journal of Dermatology, 184 (3). pp. 437-449. ISSN 0007-0963
Paller, A.S., Siegfried, E.C., Simpson, E.L. et al. (12 more authors) (2021) A phase 2, open‐label study of single‐dose dupilumab in children aged 6 months to <6 years with severe uncontrolled atopic dermatitis: pharmacokinetics, safety and efficacy. Journal of the European Academy of Dermatology and Venereology, 35 (2). pp. 464-475. ISSN 0926-9959
Wollenberg, A., Christen‐Zäch, S., Taieb, A. et al. (24 more authors) (2020) ETFAD/EADV Eczema task force 2020 position paper on diagnosis and treatment of atopic dermatitis in adults and children. Journal of the European Academy of Dermatology and Venereology, 34 (12). pp. 2717-2744. ISSN 0926-9959
Paller, A.S., Siegfried, E.C., Thaçi, D. et al. (22 more authors) (2020) Efficacy and safety of dupilumab with concomitant topical corticosteroids in children 6 to 11 years old with severe atopic dermatitis: a randomized, double-blinded, placebo-controlled phase 3 trial. Journal of the American Academy of Dermatology, 83 (5). pp. 1282-1293. ISSN 0190-9622
Danby, S.G. orcid.org/0000-0001-7363-140X, Andrew, P.V., Brown, K. et al. (3 more authors) (2020) An investigation of the skin barrier restoring effects of a cream and lotion containing ceramides in a multi-vesicular emulsion in people with dry, eczema-prone, skin: The RESTORE study phase 1. Dermatology and Therapy, 10 (5). pp. 1031-1041. ISSN 2193-8210
Wollenberg, A., Flohr, C., Simon, D. et al. (30 more authors) (2020) European Task Force on Atopic Dermatitis (ETFAD) statement on severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2)-infection and atopic dermatitis. Journal of the European Academy of Dermatology and Venereology, 34 (6). e241-e242. ISSN 0926-9959
Carr, A.N., DeWitt, T., Cork, M.J. orcid.org/0000-0003-4428-2428 et al. (15 more authors) (2020) Diaper dermatitis prevalence and severity : global perspective on the impact of caregiver behavior. Pediatric Dermatology, 37 (1). pp. 130-136. ISSN 0736-8046
Cork, M.J. orcid.org/0000-0003-4428-2428, Thaçi, D., Eichenfield, L.F. et al. (19 more authors) (2020) Dupilumab in adolescents with uncontrolled moderate‐to‐severe atopic dermatitis : results from a phase IIa open‐label trial and subsequent phase III open‐label extension. British Journal of Dermatology, 182 (1). pp. 85-96. ISSN 0007-0963
Cork, M.J. orcid.org/0000-0003-4428-2428, Danby, S.G. orcid.org/0000-0001-7363-140X and Ogg, G.S. (2020) Atopic dermatitis epidemiology and unmet need in the United Kingdom. Journal of Dermatological Treatment, 31 (8). pp. 801-809. ISSN 0954-6634
Akinlade, B., Guttman-Yassky, E., de Bruin-Weller, M. et al. (25 more authors) (2019) Conjunctivitis in dupilumab clinical trials. British Journal of Dermatology, 181 (3). pp. 459-473. ISSN 0007-0963
Jabbar-Lopez, Z.K., Gurung, N., Greenblatt, D. et al. (12 more authors) (2019) Protocol for an outcome assessor-blinded pilot randomised controlled trial of an ion-exchange water softener for the prevention of atopic eczema in neonates, with an embedded mechanistic study : the softened water for eczema prevention (SOFTER) trial. BMJ Open, 9 (8).
Thyssen, J.P., de Bruin-Weller, M.S., Paller, A.S. et al. (14 more authors) (2019) Conjunctivitis in atopic dermatitis patients with and without dupilumab therapy - international eczema council survey and opinion. Journal of the European Academy of Dermatology and Venereology, 33 (7). pp. 1224-1231. ISSN 0926-9959
Cork, M.J. orcid.org/0000-0003-4428-2428, Eckert, L., Simpson, E.L. et al. (14 more authors) (2019) Dupilumab improves patient-reported symptoms of atopic dermatitis, symptoms of anxiety and depression, and health-related quality of life in moderate-to-severe atopic dermatitis: analysis of pooled data from the randomized trials SOLO 1 and SOLO 2. Journal of Dermatological Treatment. ISSN 0954-6634
Leshem, Y.A., Bissonnette, R., Paul, C. et al. (5 more authors) (2019) Optimization of placebo use in clinical trials with systemic treatments for atopic dermatitis: an International Eczema Council survey-based position statement. Journal of the European Academy of Dermatology and Venereology , 33 (5). pp. 807-815. ISSN 0926-9959
Simpson, E.L., Reynolds, N.J., Flohr, C. et al. (5 more authors) (2018) Response to "Comment on: 'When does atopic dermatitis warrant systemic therapy? Recommendations from an expert panel of the International Eczema Council'''. Journal of The American Academy of Dermatology, 79 (2). E25-E26. ISSN 0190-9622
Byers, R.A., Maiti, R., Danby, S.G. orcid.org/0000-0001-7363-140X et al. (6 more authors) (2018) Sub-clinical assessment of atopic dermatitis severity using angiographic optical coherence tomography. Biomedical Optics Express, 9 (4). pp. 2001-2017.
Simpson, E.L., Bruin-Weller, M., Flohr, C. et al. (26 more authors) (2017) When does atopic dermatitis warrant systemic therapy? Recommendations from an expert panel of the International Eczema Council. Journal of The American Academy of Dermatology, 77 (4). pp. 623-633. ISSN 0190-9622
Koh, M.J-A., Giam, Y.C., Liew, H.M. et al. (8 more authors) (2017) Comparison of the simple patient-centric atopic dermatitis scoring system PEST with SCORAD in young children using a ceramide dominant therapeutic moisturizer. Dermatology and Therapy, 7 (3). pp. 383-393. ISSN 2193-8210
Chalmers, J.R. orcid.org/0000-0002-2281-7367, Haines, R.H., Mitchell, E.J. et al. (11 more authors) (2017) Effectiveness and cost-effectiveness of daily all-over-body application of emollient during the first year of life for preventing atopic eczema in high-risk children (The BEEP trial): protocol for a randomised controlled trial. Trials, 18 (1). 343.
Danby, S.G., Wigley, A., Cork, M.J. et al. (1 more author) (2017) Biologic Treatments for Atopic Eczema: Anti IL-4 and IL-13 biologics. Exchange: National Eczema Society Members' Magazine (163). pp. 11-18.
Danby, S.G. orcid.org/0000-0001-7363-140X, Chalmers, J., Brown, K. et al. (2 more authors) (2016) A functional mechanistic study of the effect of emollients on the structure and function of the skin barrier. British Journal of Dermatology, 175 (5). pp. 1011-1019. ISSN 0007-0963
Chittock, J. orcid.org/0000-0002-1595-7441, Cooke, A., Lavender, T. et al. (5 more authors) (2016) Development of stratum corneum chymotrypsin-like protease activity and natural moisturising factors from birth to 4 weeks of age compared to adults. British Journal of Dermatology, 175 (4). pp. 713-720. ISSN 0007-0963
Simpson, E.L., Bieber, T., Guttman-Yassky, E. et al. (23 more authors) (2016) Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis. The New England Journal of Medicine. ISSN 0028-4793
Albenali, L.H., Danby, S., Moustafa, M. et al. (4 more authors) (2016) Vitamin D and antimicrobial peptide levels in patients with atopic dermatitis and atopic dermatitis complicated by eczema herpeticum: A pilot study. Journal of Allergy and Clinical Immunology. ISSN 0091-6749
Blume-Peytavi, U., Lavender, T., Jenerowicz, D. et al. (4 more authors) (2016) Recommendations from a European Roundtable Meeting on Best Practice Healthy Infant Skin Care. Pediatric Dermatology, 33 (3). pp. 311-321. ISSN 0736-8046
Mason, J.M., Carr, J., Buckley, C. et al. (4 more authors) (2013) Improved emollient use reduces atopic eczema symptoms and is cost neutral in infants: before-and-after evaluation of a multifaceted educational support programme. BMC Dermatol, 13 (7). ISSN 1471-5945
Lavender, T., Bedwell, C., Roberts, S.A. et al. (4 more authors) (2013) Randomized, Controlled Trial Evaluating a Baby Wash Product on Skin Barrier Function in Healthy, Term Neonates. Journal of Obstetric, Gynecologic & Neonatal Nursing, 42 (2). pp. 203-214. ISSN 0884-2175
Tsoi, L.C., Spain, S.L., Knight, J. et al. (199 more authors) (2012) Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nature Genetics, 44 (12). pp. 1341-1348. ISSN 1061-4036
Lavender, T., Bedwell, C., O'Brien, E. et al. (3 more authors) (2011) Infant skin-cleansing product versus water: A pilot randomized, assessor-blinded controlled trial. BMC Pediatrics, 11. 35. ISSN 1471-2431
Vasilopoulos, Y., Walters, K., Cork, M.J. et al. (3 more authors) (2008) Association analysis of the skin barrier gene cystatin A at the PSORS5 locus in psoriatic patients: evidence for interaction between PSORS1 and PSORS5'. European Journal of Human Genetics, 16 (8). pp. 1002-1009. ISSN 1018-4813
Mason, J., Mason, A.R. and Cork, M.J. (2002) Topical preparations for the treatment of psoriasis: a systematic review. British Journal of Dermatology, 146 ( 3). pp. 351-364. ISSN 0007-0963
Proceedings Paper
Cork, M.J. orcid.org/0000-0003-4428-2428, Eichenfield, L.F., Blauvelt, A. et al. (9 more authors) (2019) 605 Efficacy and safety of dupilumab in adolescent patients with moderate-to-severe atopic dermatitis. In: Journal of Investigative Dermatology. Society for Investigative Dermatology (SID) 2019, 08-11 May 2019, Hilton Chicago, Chicago, Illinois. Elsevier , S104-S104.
Chittock, J. orcid.org/0000-0002-1595-7441, Brown, K., Cork, M.J. et al. (1 more author) (2018) Quantification of natural moisturizing factors at the skin surface using a portable infrared spectrometer device: a pilot, calibration model. In: British Journal of Dermatology. The 10th George Rajka International Symposium on Atopic Dermatitis, 11-13 Apr 2018, Utrecht, Netherlands. Wiley , E35-E36.
Byers, R.A., Maiti, R., Danby, S.G. orcid.org/0000-0001-7363-140X et al. (6 more authors) (2017) Characterizing the microcirculation of atopic dermatitis using angiographic optical coherence tomography. In: Choi, B., Zeng, H. and Kollias, N., (eds.) Proceedings of SPIE. SPIE BIOS 2017, 28 Jan - 02 Feb 2017, San Francisco, California. Society of Photo-optical Instrumentation Engineers . ISBN 9781510605152