Items where authors include "Colman, MA"

Article

Holmes, M, Hurley, ME orcid.org/0000-0003-0553-3079, Sheard, TMD orcid.org/0000-0003-4940-3188 et al. (3 more authors) (2022) Increased SERCA2a sub-cellular heterogeneity in right-ventricular heart failure inhibits excitation-contraction coupling and modulates arrhythmogenic dynamics. Philosophical Transactions of the Royal Society B: Biological Sciences, 377 (1864). 20210317. ISSN 0962-8436

Colman, MA orcid.org/0000-0003-2817-8508 (2020) The multiple mechanisms of spatially discordant alternans in the heart. Biophysical Journal, 118 (10). pp. 2336-2338. ISSN 0006-3495

Colman, MA orcid.org/0000-0003-2817-8508, Holmes, M, Whittaker, DG et al. (2 more authors) (2020) Multi-scale approaches for the simulation of cardiac electrophysiology: I - sub-cellular and stochastic calcium dynamics from cell to organ. Methods. ISSN 1046-2023

Benson, AP orcid.org/0000-0003-4679-9842, Stevenson-Cocks, HJ orcid.org/0000-0003-1044-3545, Whittaker, DG et al. (2 more authors) (2020) Multi-scale approaches for the simulation of cardiac electrophysiology: II - tissue-level structure and function. Methods. ISSN 1046-2023

Whittaker, DG orcid.org/0000-0002-2757-5491, Benson, AP orcid.org/0000-0003-4679-9842, Teh, I et al. (2 more authors) (2019) Investigation of the Role of Myocyte Orientations in Cardiac Arrhythmia Using Image-Based Models. Biophysical Journal, 117 (12). pp. 2396-2408. ISSN 0006-3495

Colman, MA orcid.org/0000-0003-2817-8508 (2019) Arrhythmia mechanisms and spontaneous calcium release: Bi-directional coupling between re-entrant and focal excitation. PLoS Computational Biology, 15 (8). e1007260. ISSN 1553-734X

Kettlewell, S, Saxena, P, Dempster, J et al. (4 more authors) (2019) Dynamic‐clamping human and rabbit atrial calcium current: narrowing ICaL window abolishes early afterdepolarisations. Journal of Physiology, 597 (14). pp. 3619-3638. ISSN 0022-3751

Perez Alday, EA, Whittaker, DG, Benson, AP orcid.org/0000-0003-4679-9842 et al. (1 more author) (2019) Effects of Heart Rate and Ventricular Wall Thickness on Non-invasive Mapping: An in silico Study. Frontiers in Physiology, 10 (308). ISSN 1664-042X

Whittaker, DG orcid.org/0000-0002-2757-5491, Colman, MA orcid.org/0000-0003-2817-8508, Ni, H et al. (2 more authors) (2018) Human Atrial Arrhythmogenesis and Sinus Bradycardia in KCNQ1-Linked Short QT Syndrome: Insights From Computational Modelling. Frontiers in Physiology, 9. 1402. ISSN 1664-042X

Colman, MA orcid.org/0000-0003-2817-8508, Saxena, P, Kettlewell, S et al. (1 more author) (2018) Description of the Human Atrial Action Potential Derived From a Single, Congruent Data Source: Novel Computational Models for Integrated Experimental-Numerical Study of Atrial Arrhythmia Mechanisms. Frontiers in Physiology, 9. 1211. ISSN 1664-042X

Colman, MA orcid.org/0000-0003-2817-8508, Perez Alday, EA, Holden, AV et al. (1 more author) (2017) Trigger versus Substrate: Multi-Dimensional Modulation of QT-Prolongation Associated Arrhythmic Dynamics by a hERG Channel Activator. Frontiers in Physiology, 8. 757. ISSN 1664-042X

Colman, MA orcid.org/0000-0003-2817-8508, Pinali, C, Trafford, AW et al. (2 more authors) (2017) A computational model of spatio-temporal cardiac intracellular calcium handling with realistic structure and spatial flux distribution from sarcoplasmic reticulum and t-tubule reconstructions. PLOS Computational Biology, 13 (8). e1005714. e1005714-e1005714. ISSN 1553-734X

Colman, MA orcid.org/0000-0003-2817-8508, Ni, H, Liang, B et al. (2 more authors) (2017) In silico assessment of genetic variation in KCNA5 reveals multiple mechanisms of human atrial arrhythmogenesis. PLoS Computational Biology, 13 (6). e1005587. ISSN 1553-734X

Alday, EAP, Colman, MA orcid.org/0000-0003-2817-8508, Langley, P et al. (1 more author) (2017) Novel non-invasive algorithm to identify the origins of re-entry and ectopic foci in the atria from 64-lead ECGs: A computational study. PLoS Computational Biology, 13 (3). e1005270. ISSN 1553-734X

Varela, M, Colman, MA orcid.org/0000-0003-2817-8508, Hancox, JC et al. (1 more author) (2016) Atrial Heterogeneity Generates Re-entrant Substrate during Atrial Fibrillation and Anti-arrhythmic Drug Action: Mechanistic Insights from Canine Atrial Models. PLOS Computational Biology, 12 (12). e1005245. ISSN 1553-734X

Morgan, R, Colman, MA orcid.org/0000-0003-2817-8508, Chubb, H et al. (2 more authors) (2016) Slow Conduction in the Border Zones of Patchy Fibrosis Stabilizes the Drivers for Atrial Fibrillation: Insights from Multi-Scale Human Atrial Modeling. Frontiers in Physiology, 7. 474. ISSN 1664-042X

Perez Alday, EA, Ni, H, Zhang, C et al. (3 more authors) (2016) Comparison of electric- and magnetic-cardiograms produced by myocardial ischemia in models of the human ventricle and torso. PLoS ONE, 11 (8). ISSN 1932-6203

Book Section

Colman, MA orcid.org/0000-0003-2817-8508 and Holden, AV (2019) Modeling the heart. In: Encyclopedia of Biophysics. Springer .

Proceedings Paper

Holmes, M, Benson, AP orcid.org/0000-0003-4679-9842, Aslanidi, OV et al. (1 more author) (2019) Investigating Calcium-Mediated Arrhythmias via a Computational Model of a Rabbit Atrial Myocyte. In: Computing in Cardiology. 2018 Computing in Cardiology Conference (CinC), 23-26 Sep 2018, Maastricht, Netherlands. IEEE . ISBN 9781728109589

Stevenson-Cocks, HJ orcid.org/0000-0003-1044-3545, Colman, MA orcid.org/0000-0003-2817-8508, White, E orcid.org/0000-0002-3954-9792 et al. (1 more author) (2019) Inward Rectifier Current Downregulation Promotes Spontaneous Calcium Release in a Novel Model of Rat Ventricular Electrophysiology. In: Computing in Cardiology. 2018 Computing in Cardiology Conference (CinC), 23-26 Sep 2018, Maastricht, Netherlands. IEEE . ISBN 9781728109589

Whittaker, DG orcid.org/0000-0002-2757-5491, Benson, AL orcid.org/0000-0003-4679-9842, Teh, I et al. (2 more authors) (2019) Role of cardiac microstructure variability on ventricular arrhythmogenesis. In: Computing in Cardiology. 20189 Computing in Cardiology Conference (CinC), 23-26 Sep 2018, Maastricht, Netherlands. IEEE . ISBN 9781728109589

Atkinson, L, Basharat, A, Benson, AP orcid.org/0000-0003-4679-9842 et al. (4 more authors) (2017) Computational Modelling of Cardiac Electrophysiological Changes in Malarial Fever. In: Computing in Cardiology. Computing in Cardiology, 11-14 Sep 2016, Vancouver, Canada. IEEE , pp. 1097-1100. ISBN 978-1-5090-0895-7

Alday, EAP, Colman, MA orcid.org/0000-0003-2817-8508 and Zhang, H (2017) Reconstruction of atrial ectopic focal and Re-entrant excitations from body surface potentials. Insights from 3D virtual human atria and torso. In: Computing in Cardiology 2016 (CinC 2016). CinC 2016, 11-14 Sep 2016, Vancouver, Canada. IEEE , pp. 701-704. ISBN 9781509008964

Jones, GM, Zhang, H and Colman, MA orcid.org/0000-0003-2817-8508 (2017) The effect of bioenergetic impairment of cytosolic processes in spatio-temporal Ca²⁺ dynamics in a three-dimensional cardiomyocyte model. In: Computing in Cardiology 2016 (CinC 2016). CinC 2016, 11-14 Sep 2016, Vancouver, Canada. IEEE , pp. 825-828. ISBN 9781509008964

Colman, MA orcid.org/0000-0003-2817-8508, Sarathy, PP, MacQuiaide, N et al. (1 more author) (2017) A new model of the human atrial myocyte with variable T-tubule organization for the study of atrial fibrillation. In: Computing in Cardiology 2016 (CinC 2016). CinC 2016, 11-14 Sep 2016, Vancouver, Canada. IEEE , pp. 221-224. ISBN 9781509008964