Items where authors include "Choi, J"

Article

Long, E, Yin, J, Funderburk, KM et al. (20 more authors) (2022) Massively parallel reporter assays and variant scoring identified functional variants and target genes for melanoma loci and highlighted cell-type specificity. American Journal of Human Genetics, 109 (12). pp. 2210-2229. ISSN 0002-9297

Castaneda-Garcia, C, Iyer, V, Nsengimana, J et al. (11 more authors) (2022) Defining novel causal SNPs and linked phenotypes at melanoma-associated loci. Human Molecular Genetics, 31 (17). pp. 2845-2856. ISSN 0964-6906

Choi, J, Bokhove, O, Kalogirou, A et al. (1 more author) (2022) Numerical Experiments on Extreme Waves Through Oblique–Soliton Interactions. Water Waves, 4 (2). pp. 139-179. ISSN 2523-367X

Lucken, K, O'Regan, L, Choi, J et al. (5 more authors) (2022) EML4-ALK Variant 3 Promotes Mitotic Errors and Spindle Assembly Checkpoint Deficiency Leading to Increased Microtubule Poison Sensitivity. Molecular Cancer Research, 20 (6). pp. 854-866. ISSN 1541-7786

Lucken, K, O'Regan, L, Choi, J et al. (5 more authors) (2022) EML4-ALK Variant 3 Promotes Mitotic Errors and Spindle Assembly Checkpoint Deficiency Leading to Increased Microtubule Poison Sensitivity. Molecular Cancer Research, 20 (6). pp. 854-866. ISSN 1541-7786

Sampson, J orcid.org/0000-0002-0147-6014, Ju, H-M, Song, J-Y et al. (3 more authors) (2022) A Polytherapy Strategy Using Vincristine and ALK Inhibitors to Sensitise EML4-ALK-Positive NSCLC. Cancers, 14 (3). 779. ISSN 2072-6694

Sampson, J orcid.org/0000-0002-0147-6014, Richards, MW orcid.org/0000-0003-1108-2825, Choi, J et al. (2 more authors) (2021) Phase‐separated foci of EML4‐ALK facilitate signalling and depend upon an active kinase conformation. EMBO Reports, 22 (12). e53693. ISSN 1469-221X

Zhang, T, Choi, J, Dilshat, R et al. (14 more authors) (2021) Cell-type-specific meQTLs extend melanoma GWAS annotation beyond eQTLs and inform melanocyte gene-regulatory mechanisms. American Journal of Human Genetics (AJHG), 108 (9). pp. 1631-1646. ISSN 0002-9297

Xu, M, Mehl, L, Zhang, T et al. (25 more authors) (2021) A UVB-responsive common variant at chromosome band 7p21.1 confers tanning response and melanoma risk via regulation of the aryl hydrocarbon receptor, AHR. American journal of human genetics, 108 (9). pp. 1611-1630. ISSN 0002-9297

Tanaka, M, Hayashi, M, Roach, L et al. (8 more authors) (2021) Synthesis of near-infrared absorbing triangular Au nanoplates using biomineralisation peptides. Acta Biomaterialia, 131. pp. 519-531. ISSN 1742-7061

Park, JY, Choi, JY, Choi, J et al. (90 more authors) (2021) Gene-environment interactions relevant to estrogen and risk of breast cancer: Can gene-environment interactions be detected only among candidate snps from genome-wide association studies? Cancers, 13 (10). 2370. ISSN 2072-6694

Choi, J, Zhang, T, Vu, A et al. (24 more authors) (2020) Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma. Nature Communications, 11 (1). 2718. ISSN 2041-1723

Landi, MT, Bishop, DT orcid.org/0000-0002-8752-8785, MacGregor, S et al. (158 more authors) (2020) Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility. Nature Genetics, 52 (5). pp. 494-504. ISSN 1061-4036

O'Regan, L, Barone, G, Adib, R et al. (10 more authors) (2020) EML4-ALK V3 oncogenic fusion proteins promote microtubule stabilization and accelerated migration through NEK9 and NEK7. Journal of Cell Science. jcs.241505. jcs.241505-jcs.241505. ISSN 0021-9533

Zhang, T, Choi, J, Kovacs, MA et al. (15 more authors) (2018) Cell-type–specific eQTL of primary melanocytes facilitates identification of melanoma susceptibility genes. Genome Research, 28 (11). pp. 1621-1635. ISSN 1088-9051

Fang, J, Jia, J, Makowski, M et al. (38 more authors) (2018) Publisher correction: Functional characterization of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148. Nature Communications, 9. p. 16159.

Choi, J, Xu, M, Makowski, MM et al. (16 more authors) (2017) A common intronic variant of PARP1 confers melanoma risk and mediates melanocyte growth via regulation of MITF. Nature Genetics, 49 (9). pp. 1287-1413. ISSN 1061-4036

Scelo, G, Purdue, MP, Brown, KM et al. (120 more authors) (2017) Genome-wide association study identifies multiple risk loci for renal cell carcinoma. Nature Communications, 8. 15724. ISSN 2041-1723

Fang, J, Jia, J, Makowski, M et al. (41 more authors) (2017) Functional characterisation of a multi-cancer risk locus on chr5p15.33 reveals regulation of TERT by ZNF148. Nature Communications, 8. 15034. ISSN 2041-1723

Woo, CG, Seo, S, Kim, SW et al. (8 more authors) (2017) Differential protein stability and clinical responses of EML4 - ALKfusion variants to various ALK inhibitors in advanced ALK - rearranged non-small cell lung cancer. Annals of Oncology, 28 (4). mdw693. pp. 791-797. ISSN 0923-7534

Bayliss, R orcid.org/0000-0003-0604-2773, Choi, J, Fennell, DA et al. (2 more authors) (2016) Molecular mechanisms that underpin EML4-ALK driven cancers and their response to targeted drugs. Cellular and Molecular Life Sciences, 73 (6). pp. 1209-1224. ISSN 1420-682X

Monograph

Choi, J, Zhang, T, Vu, A et al. (21 more authors) (2019) Massively parallel reporter assays combined with cell-type specific eQTL informed multiple melanoma loci and identified a pleiotropic function of HIV-1 restriction gene, MX2, in melanoma promotion. Working Paper. Cold Spring Harbor Laboratory (Submitted)