Items where authors include "Brayne, C."

Article

Wharton, S.B. orcid.org/0000-0003-2785-333X, Simpson, J.E. orcid.org/0000-0002-3753-4271, Ince, P.G. et al. (4 more authors) (2023) Insights into the pathological basis of dementia from population based neuropathology studies. Neuropathology and Applied Neurobiology, 49 (4). e12923. ISSN 0305-1846

Rajab, M.D., Jammeh, E., Taketa, T. et al. (6 more authors) (2023) Assessment of Alzheimer-related pathologies of dementia using machine learning feature selection. Alzheimer's Research & Therapy, 15. 47. ISSN 1758-9193

Nichols, E., Merrick, R., Hay, S.I. et al. (19 more authors) (2023) The prevalence, correlation, and co-occurrence of neuropathology in old age: harmonisation of 12 measures across six community-based autopsy studies of dementia. The Lancet Healthy Longevity, 4 (3). e115. ISSN 2666-7568

Nelson, P.T., Brayne, C., Flanagan, M.E. et al. (46 more authors) (2022) Frequency of LATE neuropathologic change across the spectrum of Alzheimer’s disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts. Acta Neuropathologica, 144 (1). pp. 27-44. ISSN 0001-6322

Ellmerich, S., Taylor, G.W., Richardson, C.D. et al. (7 more authors) (2021) Dementia in the older population is associated with neocortex content of serum amyloid P component. Brain Communications, 3 (4). fcab225.

Waller, R. orcid.org/0000-0001-5815-8829, Narramore, R., Simpson, J.E. orcid.org/0000-0002-3753-4271 et al. (12 more authors) (2021) Heterogeneity of cellular inflammatory responses in ageing white matter and relationship to alzheimer’s and small vessel disease pathologies. Brain Pathology, 31 (3). e12928. ISSN 1015-6305

Bury, J.J., Chambers, A., Heath, P.R. et al. (6 more authors) (2021) Type 2 diabetes mellitus-associated transcriptome alterations in cortical neurones and associated neurovascular unit cells in the ageing brain. Acta Neuropathologica Communications, 9 (1). 5.

Fadul, M.M. orcid.org/0000-0002-2208-9988, Heath, P.R., Cooper-Knock, J. orcid.org/0000-0002-0873-8689 et al. (8 more authors) (2020) Transcriptomic analysis of age-associated periventricular lesions reveals dysregulation of the immune response. International Journal of Molecular Sciences, 21 (21). 7924. ISSN 1661-6596

Breeze, P. orcid.org/0000-0002-4189-8676, Thomas, C., Thokala, P. orcid.org/0000-0003-4122-2366 et al. (3 more authors) (2020) The impact of including costs and outcomes of dementia in a health economic model to evaluate lifestyle interventions to prevent diabetes and cardiovascular disease. Medical Decision Making, 40 (7). pp. 912-923. ISSN 0272-989X

Chambers, A., Bury, J.J., Minett, T. et al. (9 more authors) (2020) Advanced glycation end product formation in human cerebral cortex increases with Alzheimer-type neuropathologic changes but is not independently associated with dementia in a population-derived aging brain cohort. Journal of Neuropathology & Experimental Neurology, 79 (9). pp. 950-958. ISSN 0022-3069

Richardson, K., Wharton, S.B. orcid.org/0000-0003-2785-333X, Grossi, C.M. et al. (12 more authors) (2020) Neuropathological correlates of cumulative benzodiazepine and anticholinergic drug use. Journal of Alzheimer's Disease, 74 (3). pp. 999-1009. ISSN 1387-2877

Fadul, M.M. orcid.org/0000-0002-2208-9988, Garwood, C.J., Waller, R. orcid.org/0000-0001-5815-8829 et al. (6 more authors) (2020) NDRG2 expression correlates with neurofibrillary tangles and microglial pathology in the ageing brain. International Journal of Molecular Sciences, 21 (1). 340. ISSN 1661-6596

Wharton, S.B., Wang, D. orcid.org/0000-0003-0068-1005, Parikh, C. et al. (3 more authors) (2019) Epidemiological pathology of Aβ deposition in the ageing brain in CFAS : addition of multiple Aβ-derived measures does not improve dementia assessment using logistic regression and machine learning approaches. Acta Neuropathologica Communications, 7 (1). 198. pp. 1-12.

Fahrenhold, M., Rakic, S., Classey, J. et al. (4 more authors) (2018) TREM2 expression in the human brain: a marker of monocyte recruitment? Brain Pathology, 28 (5). pp. 595-602. ISSN 1015-6305

Waller, R. orcid.org/0000-0001-5815-8829, Murphy, M., Garwood, C. et al. (8 more authors) (2018) Metallothionein‐I/II expression associates with the astrocyte DNA damage response and not Alzheimer‐type pathology in the aging brain. Glia. ISSN 0894-1491

Kingston, A., Wohland, P., Wittenberg, R. et al. (4 more authors) (2017) Is late-life dependency increasing or not? A comparison of the Cognitive Function and Ageing Studies (CFAS). The Lancet, 390 (10103). pp. 1676-1684. ISSN 0140-6736

Ince, P.G., Minett, T., Forster, G. et al. (3 more authors) (2017) Microinfarcts in an older population-representative brain donor cohort (MRC CFAS): Prevalence, relation to dementia and mobility, and implications for the evaluation of cerebral Small Vessel Disease. Neuropathology and Applied Neurobiology, 43 (5). pp. 409-418. ISSN 0305-1846

Davis, D.H.J., Muniz-Terrera, G., Keage, H.A.D. et al. (21 more authors) (2017) Association of delirium with cognitive decline in late life: A neuropathologic study of 3 population-based cohort studies. JAMA Psychiatry, 74 (3). pp. 244-251. ISSN 2168-622X

Bowman, K., Delgado, J., Henley, W.E. et al. (8 more authors) (2016) Obesity in Older People With and Without Conditions Associated With Weight Loss: Follow-up of 955,000 Primary Care Patients. Journals of Gerontology, Series A. ISSN 1079-5006

Taga, M., Minett, T., Classey, J. et al. (6 more authors) (2016) Metaflammasome components in the human brain: a role in dementia with alzheimer's pathology? Brain Pathology. ISSN 1015-6305

Minett, T., Classey, J., Matthews, F.E. et al. (7 more authors) (2016) Microglial immunophenotype in dementia with Alzheimer's pathology. Journal of Neuroinflammation, 13. ARTN 135. ISSN 1742-2094

Matthews, F.E., Stephan, B.C.M., Robinson, L. et al. (22 more authors) (2016) A two decade dementia incidence comparison from the Cognitive Function and Ageing Studies I and II. Nature Communications, 7. 11398. p. 11398. ISSN 2041-1723

Wharton, S.B., Minett, T., Drew, D. et al. (5 more authors) (2016) Epidemiological pathology of Tau in the ageing brain: application of staging for neuropil threads (BrainNet Europe protocol) to the MRC cognitive function and ageing brain study. Acta Neuropathol Communications, 4. 11. ISSN 2051-5960

Fluteau, A., Ince, P.G., Minett, T. et al. (10 more authors) (2015) The nuclear retention of transcription factor FOXO3a correlates with a DNA damage response and increased glutamine synthetase expression by astrocytes suggesting a neuroprotective role in the ageing brain. Neuroscience Letters, 609. pp. 11-17. ISSN 0304-3940

Peuralinna, T., Myllykangas, L., Oinas, M. et al. (14 more authors) (2015) Genome-wide association study of neocortical Lewy-related pathology. Annals of Clinical and Translational Neurology, 2 (9). pp. 920-931.

Al-Mashhadi, S., Simpson, J.E., Heath, P.R. et al. (6 more authors) (2015) Oxidative Glial Cell Damage Associated with White Matter Lesions in the Aging Human Brain. Brain Pathology, 25 (5). pp. 565-574. ISSN 1015-6305

Simpson, J.E., Ince, P.G., Minett, T. et al. (9 more authors) (2015) Neuronal DNA damage response-associated dysregulation of signalling pathways and cholesterol metabolism at the earliest stages of Alzheimer-type pathology. Neuropathology and Applied Neurobiology. ISSN 0305-1846

Simpson, J.E., Ince, P.G., Matthews, F.E. et al. (7 more authors) (2015) A neuronal DNA damage response is detected at the earliest stages of Alzheimer's neuropathology and correlates with cognitive impairment in the Medical Research Council's Cognitive Function and Ageing Study ageing brain cohort. Neuropathology and Applied Neurobiology, 41 (4). pp. 483-496. ISSN 0305-1846

Zaccai, J., Brayne, C., Matthews, F.E. et al. (2 more authors) (2015) Alpha-synucleinopathy and neuropsychological symptoms in a population-based cohort of the elderly. Alzheimer's Research & Therapy, 7. ARTN 19. ISSN 1758-9193

Mathur, R., Ince, P.G., Minett, T. et al. (7 more authors) (2015) A Reduced Astrocyte Response to beta-Amyloid Plaques in the Ageing Brain Associates with Cognitive Impairment. PLOS ONE, 10 (2). e0118463. ISSN 1932-6203

Mathur, R., Ince, P.G., Minett, T. et al. (6 more authors) (2015) A Reduced Astrocyte Response to β-Amyloid Plaques in the Ageing Brain Associates with Cognitive Impairment. PLoS One, 10 (2). e0118463. ISSN 1932-6203

Highley, J.R. orcid.org/0000-0002-4969-6526, Gebril, O.H., Simpson, J.E. et al. (9 more authors) (2014) Axonal Preservation in Deep Subcortical White Matter Lesions in the Ageing Brain. Journal of Aging Science, 2 (1).

Matthew, F.E., Brayne, C., Lowe, J. et al. (3 more authors) (2009) Epidemiological pathology of dementia: attributable-risks at death in the medical research council cognitive function and ageing study. PLOS Medicine , 6 (11). Art no.e1000180 . ISSN 1549-1277

Byford, M., Brayne, C., McKeith, I. et al. (3 more authors) (2009) Lewy bodies and neuronal loss in subcortical areas and disability in non-demented older people: a population based neuropathological cohort study. BMC Geriatrics, 9 (1). p. 22. ISSN 1471-2318

Keage, H., Carare, R., Friedland, R. et al. (6 more authors) (2009) Population studies of sporadic cerebral amyloid angiopathy and dementia: a systematic review. BMC Neurology, 9 (1). p. 3. ISSN 1471-2377

Zaccai, J., Ince, P. and Brayne, C. (2006) Population-based neuropathological studies of dementia: design, methods and areas of investigation – a systematic review. BMC Neurology, 6 (2). ISSN 1471-2377

Matthews, F., Brayne, C. and Medical Research Council, Cognitive Function and Ageing Study Investigators (2005) The incidence of dementia in England and Wales: findings from the five identical sites of the MRC CFA Study. PLoS Medicine, 2 (8). e193. ISSN 1549-1277