Items where authors include "Berglund, U.W."
Up a levelArticle
Eding, C.B., Köhler, I., Verma, D. et al. (8 more authors) (2021) MTH1 inhibitors for the treatment of psoriasis. Journal of Investigative Dermatology, 141 (8). 2037-2048.e4. ISSN 0022-202X
Zhao, Z., Gad, H. orcid.org/0000-0001-6530-1443, Benitez-Buelga, C. et al. (8 more authors) (2021) NEIL3 prevents senescence in hepatocellular carcinoma by repairing oxidative lesions at telomeres during mitosis. Cancer Research, 81 (15). pp. 4079-4093. ISSN 0008-5472
Rehling, D., Zhang, S.M., Jemth, A.-S. et al. (15 more authors) (2021) Crystal structures of NUDT15 variants enabled by a potent inhibitor reveal the structural basis for thiopurine sensitivity. Journal of Biological Chemistry, 296. 100568. ISSN 0021-9258
Oksvold, M.P., Berglund, U.W., Gad, H. orcid.org/0000-0001-6530-1443 et al. (11 more authors) (2021) Karonudib has potent anti-tumor effects in preclinical models of B-cell lymphoma. Scientific Reports, 11 (1). 6317.
Visnes, T., Benítez-Buelga, C., Cázares-Körner, A. et al. (43 more authors) (2020) Targeting OGG1 arrests cancer cell proliferation by inducing replication stress. Nucleic Acids Research, 48 (21). pp. 12234-12251. ISSN 0305-1048
Zhang, S.M., Desroses, M., Hagenkort, A. et al. (34 more authors) (2020) Development of a chemical probe against NUDT15. Nature Chemical Biology, 16 (10). pp. 1120-1128. ISSN 1552-4450
Scaletti, E.R., Vallin, K.S., Bräutigam, L. et al. (5 more authors) (2020) MutT homologue 1 (MTH1) removes N6-methyl-dATP from the dNTP pool. Journal of Biological Chemistry, 295 (15). pp. 4761-4772. ISSN 0021-9258
Moukengue, B., Brown, H.K., Charrier, C. et al. (11 more authors) (2020) TH1579, MTH1 inhibitor, delays tumour growth and inhibits metastases development in osteosarcoma model. EBioMedicine, 53. 102704. ISSN 2352-3964
Rudd, S.G. orcid.org/0000-0002-4368-3855, Gad, H., Amaral, N. et al. (6 more authors) (2019) MTH1 inhibitor TH588 induces mitosis-dependent accumulation of genomic 8-oxodG and disturbs mitotic progression. bioRxiv. (Submitted)
Lallo, A., Gulati, S., Schenk, M.W. et al. (12 more authors) (2019) Ex vivo culture of cells derived from circulating tumour cell xenograft to support small cell lung cancer research and experimental therapeutics. British Journal of Pharmacology, 176 (3). pp. 436-450. ISSN 0007-1188
Einarsdottir, B.O., Karlsson, J., Söderberg, E.M.V. et al. (16 more authors) (2018) A patient-derived xenograft pre-clinical trial reveals treatment responses and a resistance mechanism to karonudib in metastatic melanoma. Cell Death and Disease, 9 (8). 810. ISSN 2041-4889
Pudelko, L., Rouhi, P., Sanjiv, K. et al. (10 more authors) (2017) Glioblastoma and glioblastoma stem cells are dependent on functional MTH1. Oncotarget, 8 (49). pp. 94671-84684.
Tsuber, V., Kadamov, Y., Brautigam, L. et al. (2 more authors) (2017) Mutations in cancer cause gain of cysteine, histidine, and tryptophan at the expense of a net loss of arginine on the proteome level. Biomolecules, 7 (3). 49. ISSN 2218-273X
Carter, M., Jemth, A.-S., Hagenkort, A. et al. (10 more authors) (2015) Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2. Nature Communications, 6. 7871.
Proceedings Paper
Sanjiv, K., Gad, H., Rudd, S. et al. (15 more authors) (2016) Polymerase kappa determines the sensitivity of MTH1 inhibitors to cisplatin-resistant cell. In: Cancer Research. AACR 107th Annual Meeting 2016, 16-20 Apr 2016, New Orleans, LA, USA. American Association for Cancer Research .