Items where authors include "Allen, S.P."

Article

Allen, S.P. orcid.org/0000-0003-4418-7375, Al Sultan, A., Kabucho Kibirige, E. et al. (13 more authors) (2023) A Y374X TDP43 truncation leads to an altered metabolic profile in amyotrophic lateral sclerosis fibroblasts driven by pyruvate and TCA cycle intermediate alterations. Frontiers in Aging Neuroscience, 15. 1151848. ISSN 1663-4365

Cooper‐Knock, J., Julian, T.H., Feneberg, E. et al. (15 more authors) (2022) Atypical TDP-43 protein expression in an ALS pedigree carrying a p.Y374X truncation mutation in TARDBP. Brain Pathology. e13104. ISSN 1015-6305

Boddy, S., Islam, M. orcid.org/0000-0002-2296-0120, Moll, T. et al. (17 more authors) (2022) Unbiased metabolome screen leads to personalized medicine strategy for amyotrophic lateral sclerosis. Brain Communications, 4 (2). fcac069. ISSN 2632-1297

Hall, B., George, J.G. and Allen, S.P. (2022) Adenosine deaminase, not immune to a mechanistic rethink in central nervous system disorders? Histology and Histopathology, 37 (3). pp. 189-212. ISSN 0213-3911

Gerou, M., Hall, B., Woof, R. et al. (5 more authors) (2021) Amyotrophic lateral sclerosis alters the metabolic aging profile in patient derived fibroblasts. Neurobiology of Aging, 105. pp. 64-77. ISSN 0197-4580

Lee, J.A.K., Hall, B., Allsop, J. et al. (2 more authors) (2021) Lipid metabolism in astrocytic structure and function. Seminars in Cell & Developmental Biology, 112. pp. 123-136. ISSN 1084-9521

Bell, S.M., Burgess, T., Lee, J. et al. (3 more authors) (2020) Peripheral glycolysis in neurodegenerative diseases. International Journal of Molecular Sciences, 21 (23). 8924. ISSN 1661-6596

Allen, S.P., Seehra, R.S., Heath, P.R. et al. (6 more authors) (2020) Transcriptomic analysis of human astrocytes in vitro reveals hypoxia-induced mitochondrial dysfunction, modulation of metabolism, and dysregulation of the immune response. International Journal of Molecular Sciences, 21 (21). 8028. ISSN 1422-0067

Floare, M.-L. and Allen, S.P. (2020) Why TDP-43? Why not? Mechanisms of metabolic dysfunction in amyotrophic lateral sclerosis. Neuroscience Insights, 15. ISSN 2633-1055

Allen, S.P., Hall, B., Woof, R. et al. (16 more authors) (2019) C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis. Brain. 302. pp. 1-20. ISSN 0006-8950

Allen, S.P., Duffy, L.M., Shaw, P.J. et al. (1 more author) (2015) Altered age-related changes in bioenergetic properties and mitochondrial morphology in fibroblasts from sporadic amyotrophic lateral sclerosis patients. Neurobiology of Aging, 36 (10). pp. 2893-2903. ISSN 0197-4580

Raman, R., Allen, S.P., Goodall, E.F. et al. (11 more authors) (2015) Gene expression signatures in motor neurone disease fibroblasts reveal dysregulation of metabolism, hypoxia-response and RNA processing functions. Neuropathology and Applied Neurobiology, 41 (2). pp. 201-226. ISSN 0305-1846

Richardson, K., Allen, S.P., Mortiboys, H.J. et al. (5 more authors) (2013) The Effect of SOD1 Mutation on Cellular Bioenergetic Profile and Viability in Response to Oxidative Stress and Influence of Mutation-Type. PLoS ONE, 8 (6). e68256. ISSN 1932-6203

Proceedings Paper

Allen, S.P., Hall, B., Castelli, L. orcid.org/0000-0003-3620-4219 et al. (11 more authors) (2018) Inosine reverses motor neuron toxicity observed in amyotrophic lateral sclerosis patient astrocytes with an adenosine deaminase deficiency. In: Biochimica et Biophysica Acta (BBA) - Bioenergetics. 20th European Bioenergetics Conference, 25-30 Aug 2018, Budapest, Hungary. Elsevier BV , e23-e23.