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Number of items at this level: 82.


Ariza, A, Tanner, SJ, Walter, CT, Dent, KC, Shepherd, DA, Wu, W, Matthews, SV, Hiscox, JA, Green, TJ, Luo, M, Elliott, RM, Fooks, AR, Ashcroft, AE, Stonehouse, NJ, Ranson, NA, Barr, JN and Edwards, TA (2013) Nucleocapsid protein structures from orthobunyaviruses reveal insight into ribonucleoprotein architecture and RNA polymerization. Nucleic Acids Research, 41 (11). 5912 - 5926 (15). ISSN 0305-1048

Ashcroft, A.E., Brinker, A., Coyle, J.E., Weber, F., Kaiser, M., Moroder, L., Parsons, M.R., Jager, J., Hartl, U.F., Hayer-Hartl, M. and Radford, S.E. (2002) Structural Plasticity and Noncovalent Substrate Binding in the GroEL Apical Domain. A study using electrospray ionization mass spectrometry and fluorescence binding studies. Journal of Biological Chemistry, 277 (36). 33115-33126. ISSN 1083-351X


Banushkina, PV and Krivov, SV (2013) High-Resolution Free-Energy Landscape Analysis of α-Helical Protein Folding: HP35 and Its Double Mutant. Journal of Chemical Theory and Computation, 9 (12). 5257 - 5266. ISSN 1549-9618

Belyaeva, TA, Nicol, C, Cesur, O, Travé, G, Blair, GE and Stonehouse, NJ (2014) An RNA aptamer targets the PDZ-binding motif of the HPV16 E6 oncoprotein. Cancers, 6 (3). 1553 - 1569. ISSN 2072-6694

Bevington, S and Boyes, J (2013) Transcription-coupled eviction of histones H2A/H2B governs V(D)J recombination. The EMBO Journal, 32 (10). 1381 - 1392. ISSN 0261-4189

Borysik, A.J.H., Radford, S.E. and Ashcroft, A.E. (2004) Co-populated Conformational Ensembles of β(2)-Microglobulin Uncovered Quantitatively by Electrospray Ionization Mass Spectrometry. Journal of Biological Chemistry, 279 (26). pp. 27069-27077. ISSN 1083-351X

Boyne, J.R., Colgan, K.J., Whitehouse, A. and Jung, J.U. (2008) Recruitment of the Complete hTREX Complex Is Required for Kaposi's Sarcoma–Associated Herpesvirus Intronless mRNA Nuclear Export and Virus Replication. PLoS Pathogens, 4 (10). e1000194. ISSN 1553-7374

Burgess, S.A., Yu, S., Walker, M.L., Hawkins, R.J., Chalovich, J.M. and Knight, P.J. (2007) Structures of smooth muscle myosin and heavy meromyosin in the folded, shutdown state. Journal of Molecular Biology, 372 (5). pp. 1165-1178. ISSN 0022-2836

Burgess, S.A., Walker, M.L., Sakakibara, H., Knight, P.J. and Oiwa, K. (2003) Dynein structure and power stroke. Nature, 421 (6924). pp. 715-718. ISSN 0028-0836

Burnett, AD, Kendrick, J, Cunningham, JE, Hargreaves, MD, Munshi, T, Edwards, HG, Linfield, EH and Davies, AG (2010) Calculation and measurement of terahertz active normal modes in crystalline PETN. Chemphyschem, 11 (2). 368 - 378 . ISSN 1439-7641


Ceasar, SA, Hodge, A, Baker, A and Baldwin, SA (2014) Phosphate concentration and arbuscular mycorrhizal colonisation influence the growth, yield and expression of twelve PHT1 family phosphate transporters in foxtail millet (Setaria italica). PLoS ONE, 9 (9). e108459. ISSN 1932-6203

Cobb, AM, Jackson, BR, Kim, E, Bond, PL and Bowater, RP (2013) Sequence-specific and DNA structure-dependent interactions of Escherichia coli MutS and human p53 with DNA. Analytical Biochemistry, 442 (1). 51 - 61. ISSN 0003-2697

Cordy, J.M., Hussain, I., Dingwall, C., Hooper, N.M. and Turner, A.J. (2003) Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein. Proceedings of the National Academy of Sciences, 100 (20). pp. 11735-11740. ISSN 0027-8424

Cox, G, Edwards, TA and O'Neill, AJ (2013) Mutagenesis mapping of the protein-protein interaction underlying FusB-type Fusidic acid resistance. Antimicrobial Agents and Chemotherapy, 57 (10). 4640 - 4644. ISSN 0066-4804


Dobbins, B.M., Kite, P., Kindon, A., McMahon, M.J. and Wilcox, M.H. (2002) DNA fingerprinting analysis of coagulase negative staphylococci implicated in catheter related bloodstream infections. Journal of Clinical Pathology, 55 (11). pp. 824-828. ISSN 0021-9746


Edwards, S, Church, JS, Alexander, DLJ, Russell, SJ, Ingham, E, Ramshaw, JAM and Werkmeister, JA (2011) Modeling Tissue Growth Within Nonwoven Scaffolds Pores. Tissue Engineering. Part C. Methods, 17 (2). 123 - 130 . ISSN 1937-3384

El-Din, S.S., Reynolds, M.T., Ashbee, H.R., Barton, R.C. and Evans, E.G.V. (2001) An investigation into the pathogenesis of vulvo-vaginal candidosis. Sexually Transmitted Infections, 77 (3). pp. 179-183. ISSN 0148-5717

Engel, Maarten F.M. (2009) Membrane permeabilization by Islet Amyloid Polypeptide. Chemistry and Physics of Lipids, 160 (1). pp. 1-10. ISSN 0009-3084

Eves-van den Akker, S, Lilley, CJ, Ault, JR, Ashcroft, AE, Jones, JT and Urwin, PE (2014) The feeding tube of cyst nematodes: characterisation of protein exclusion. PLoS One, 9 (1). e87289. ISSN 1932-6203


Fadouloglou, V.E., Tampakaki, A.P., Glykos, N.M., Bastaki, M.N, Hadden, J.M., Phillips, S.E.V., Panopoulos, N.J. and Kokkinidis, M. (2004) Structure of HrcQ(B)-C, a conserved component of the bacterial type III secretion systems. Proceedings of the National Academy of Sciences, 101 (1). pp. 70-75. ISSN 0027-8424

Fawley, W.N. and Wilcox, M.H. (2001) Molecular epidemiology of endemic Clostridium difficile infection. Epidemiology and Infection, 126 (3). pp. 343-350. ISSN 0950-2688

Fearnley, GW, Smith, GA, Odell, AF, Latham, AM, Wheatcroft, SB, Harrison, MA, Tomlinson, DC and Ponnambalam, S (2014) Vascular endothelial growth factor A-stimulated signaling from endosomes in primary endothelial cells. Methods in Enzymology, 535. 265 - 292. ISSN 0076-6879

Figueiredo, AM, Whittaker, SB-M, Knowling, SE, Radford, SE and Moore, GR (2013) Conformational dynamics is more important than helical propensity for the folding of the all alpha-helical protein Im7. Protein Science, 22 (12). 1722 - 1738. ISSN 1469-896X

Franqueville, L., Henning, P., Magnusson, M.E., Vigne, E., Schoehn, G., Blair-Zajdel, M.E., Habib, N., Lindholm, L., Blair, G.E., Hong, S.S. and Boulanger, P. (2008) Protein crystals in adenovirus type 5-infected cells: requirements for intranuclear crystallogenesis, structural and functional analysis. PLoS ONE, 3 (8). e2894. ISSN 1932-6203

Freeman, J. and Wilcox, M.H. (2003) The effects of storage conditions on viability of Clostridium difficile vegetative cells and spores and toxin activity in human faeces. Journal of Clinical Pathology, 56 (2). pp. 126-128. ISSN 0021 - 9746


Gidalevitz, T., Biswas, C., Ding, H., Schneidman-Duhovny, D., Wolfson, H.J., Stevens, F., Radford, S.E. and Argon, Y. (2004) Identification of the N-terminal Peptide Binding Site of Glucose-regulated Protein 94. Journal of Biological Chemistry, 279 (16). pp. 16543-16552. ISSN 1083-351X


Hall, D.R., Bond, C.S., Leonard, G.A., Watt, C.I., Berry, A. and Hunter, W.N. (2002) Structure of Tagatose-1,6-bisphosphate Aldolase. Insight into chiral discrimination, mechanism, and specificity of class II aldolases. Journal of Biological Chemistry, 277 (24). pp. 22018-22024. ISSN 1083-351X

Haque, SF, Bevington, S and Boyes, JM (2013) The E<lambda>3-1 Enhancer is Essential for V(D)J Recombination of the Murine Immunoglobulin Lambda Light Chain Locus. Biochemical and Biophysical Research Communications, 441 (2). BBRC-13-5918. 482 - 487. ISSN 0006-291X

Hodkinson, JP, Radford, SE and Ashcroft, AE (2012) The role of conformational flexibility in β2-microglobulin amyloid fibril formation at neutral pH. Rapid Communications in Mass Spectrometry, 26 (16). 1783 - 1792. ISSN 0951-4198

Holloway, ZG, Velayos-Baeza, A, Howell, GJ, Levecque, C, Ponnambalam, S, Sztul, E and Monaco, AP (2013) Trafficking of the Menkes copper transporter ATP7A is regulated by clathrin-, AP-2-, AP-1-, and Rab22-dependent steps. Molecular Biology of the Cell, 24 (11). 1735 - 1748. ISSN 1059-1524

Hughes, T.A. and Jones, P.F. (2008) Regulatory RNAs: Have mRNA Untranslated Regions Joined the Party? PLoS Medicine, 5 (5). e110. ISSN 1549-1277


Jen, C.H., Michalopoulos, I., Westhead, D.R. and Meyer, P. (2005) Natural antisense transcripts with coding capacity in Arabidopsis may have a regulatory role that is not linked to double-stranded RNA degradation. Genome Biology, 6 (6(R51)). ISSN 1465-6914


Karamanos, TK, Kalverda, AP, Thompson, GS and Radford, SE (2014) Visualization of transient protein-protein interactions that promote or inhibit amyloid assembly. Molecular Cell, 55 (2). 214 - 226. ISSN 1097-2765

Krivov, SV (2013) Method to describe stochastic dynamics using an optimal coordinate. Physical Review E: Statistical, Nonlinear, and Soft Matter Physics, 88 (6). 062131. ISSN 1539-3755

Krivov, SV, Fenton, H, Goldsmith, PJ, Prasad, RK, Fisher, J and Paci, E (2014) Optimal reaction coordinate as a biomarker for the dynamics of recovery from kidney transplant. PLoS Computational Biology, 10 (6). e1003685. ISSN 1553-734X


Leney, AC, McMorran, LM, Radford, SE and Ashcroft, AE (2012) Amphipathic polymers enable the study of functional membrane proteins in the gas phase. Analytical Chemistry, 84 (22). 9841 - 9847. ISSN 1086-4377

Leney, AC, Pashley, CL, Scarff, CA, Radford, SE and Ashcroft, AE (2014) Insights into the role of the beta-2 microglobulin D-strand in amyloid propensity revealed by mass spectrometry. Molecular BioSystems, 10 (3). 412 - 420. ISSN 1742-206X

Leney, AC, Phan, G, Allen, W, Verger, D, Waksman, G, Radford, SE and Ashcroft, AE (2011) Second order rate constants of donor-strand exchange reveal individual amino acid residues important in determining the subunit specificity of pilus biogenesis. Journal of the American Society for Mass Spectrometry, 22 (7). 1214 - 1223. ISSN 1044-0305

Levesley, A, Paxton, S, Collins, R, Baker, A and Knight, C (2014) Engaging students with plant science: the plant science TREE. New Phytologist, 203 (4). 1041 - 1048. ISSN 0028-646X


McMorran, LM, Bartlett, AL, Huysmans, GHM, Radford, SE and Brockwell, DJ (2013) Dissecting the effects of periplasmic chaperones on the in vitro folding of the outer membrane protein PagP. Journal of Molecular Biology, 425 (17). 3178 - 3191. ISSN 0022-2836

McMorran, LM, Brockwell, DJ and Radford, SE (2014) Mechanistic studies of the biogenesis and folding of outer membrane proteins in vitro and in vivo: what have we learned to date? Archives of Biochemistry and Biophysics, 564. 265 - 280. ISSN 0003-9861

Modi, N. and Wilcox, M.H. (2001) Evidence for antibiotic induced Clostridium perfringens diarrhoea. Journal of Clinical Pathology, 54 (10). pp. 748-751. ISSN 0021-9746


Ndlovu, H, Ashcroft, AE, Radford, SE and Harris, SA (2013) Molecular dynamics simulations of mechanical failure in polymorphic arrangements of amyloid fibrils containing structural defects. Beilstein Journal of Nanotechnology, 4. 429 - 440. ISSN 2190-4286

Needham, C.J, Bradford, J.R., Bulpitt, A.J. and Westhead, D.R. (2007) A primer on learning in Bayesian networks for computational biology. PLoS Computational Biology, 3 (8). e129. ISSN 1553-7358

Needham, C.J., Bradford, J.R., Bulpitt, A.J., Care, M.A. and Westhead, D.R. (2006) Predicting the effect of missense mutations on protein function: analysis with Bayesian networks. BMC Bioinformatics, 7 (405). ISSN 1471-2105

Needham, C.J., Manfield, I.W., Bulpitt, A.J., Gilmartin, P.M. and Westhead, D.R. (2009) From gene expression to gene regulatory networks in Arabidopsis thaliana. BMC Systems Biology , 3 (85). ISSN 1752-0509


Paci, E., Rose, R.J., Welsh, T.S., Waksman, G., Ashcroft, A.E. and Radford, S.E. (2008) Donor-strand exchange in chaperone-assisted pilus assembly revealed in atomic detail by molecular dynamics. Journal of Molecular Biology, 375 (4). pp. 908-919. ISSN 0022-2836

Paudyal, R, Jamaluddin, A, Warren, JP, Doyle, SM, Robert, S, Warriner, SL and Baker, A (2014) Trafficking modulator TENin1 inhibits endocytosis, causes endomembrane protein accumulation at the pre-vacuolar compartment and impairs gravitropic response in Arabidopsis thaliana. Biochemical Journal, 460 (2). 177 - 185. ISSN 0264-6021

Pinney, J.W., Shirley, M.W., McConkey, G.A. and Westhead, D.R. (2005) metaSHARK: software for automated metabolic network prediction from DNA sequence and its application to the genomes of Plasmodium falciparum and Eimeria tenella. Nucleic Acids Research, 33 (4). pp. 1399-1409. ISSN 1362-4962

Preston, GW, Radford, SE, Wilson, AJ and Ashcroft, AE (2014) Analysis of amyloid nanostructures using photo-cross-linking: in situ comparison of three widely used photo-cross-linkers. ACS Chemical Biology, 9 (3). 761 - 768. ISSN 1554-8929

Pritchard, S.L., Charlton, W.L., Baker, A. and Graham, I.A. (2002) Germination and storage reserve mobilization are regulated independently in Arabidopsis. The Plant Journal, 31 (5). pp. 639-647. ISSN 0960-7412


Rimratchada, S, Paci, E, McLeish, TCB and Radford, SE (2014) The role of high-dimensional diffusive search, stabilization, and frustration in protein folding. Biophysical Journal, 106 (8). 1729 - 1740. ISSN 0006-3495

Roberts, GA, Chen, K, Bower, EKM, Madrzak, J, Woods, A, Barker, AM, Cooper, LP, White, JH, Blakely, G, Manfield, IW and Dryden, DTF (2013) Mutations of the domain forming the dimeric interface of the ArdA protein affect dimerization and antimodification activity but not antirestriction activity. The Federation of European Biochemical Societies (FEBS) Journal (280). 4903 - 4914. ISSN 1742-464X

Rose, R.J., Verger, D., Daviter, T., Remaut, H., Paci, E., Waksman, G., Ashcroft, A.E. and Radford, S.E. (2008) Unraveling the molecular basis of subunit specificity in P pilus assembly by mass spectrometry. Proceedings of the National Academy of Sciences of The United States of America, 105 (35). pp. 12873-12878.


Sarell, CJ, Karamanos, TK, White, SJ, Bunka, DH, Kalverda, AP, Thompson, GS, Barker, AM, Stockley, PG and Radford, SE (2014) Distinguishing closely related amyloid precursors using an RNA aptamer. The Journal of Biological Chemistry, 289 (39). 26859 - 26871. ISSN 0021-9258

Sarell, CJ, Stockley, PG and Radford, SE (2013) Assessing the causes and consequences of co-polymerization in amyloid formation. Prion, 7 (5). 359 - 368. ISSN 1933-6896

Scott, JNF, Kupinski, AP, Kirkham, CM, Tuma, R and Boyes, JM (2014) Tale proteins bind to both active and inactive chromatin. Biochemical Journal, 458 (1). 153 - 158. ISSN 0264-6021

Seipke, RF, Barke, J, Heavens, D, Yu, DW and Hutchings, MI (2013) Analysis of the bacterial communities associated with two ant-plant symbioses. MicrobiologyOpen, 2 (2). 276 - 283.

Seipke, RF and Hutchings, MI (2013) The regulation and biosynthesis of antimycins. Beilstein Journal of Organic Chemistry, 9. 2556 - 2563. ISSN 1860-5397

Seipke, RF, Patrick, E and Hutchings, MI (2014) Regulation of antimycin biosynthesis by the orphan ECF RNA polymerase sigma factor σ (AntA.). PeerJ, 2. e253. ISSN 2167-8359

Shepherd, DA, Ariza, A, Edwards, TA, Barr, JN, Stonehouse, NJ and Ashcroft, AE (2014) Probing Bunyavirus N protein oligomerisation using mass spectrometry. Rapid Communications in Mass Spectrometry, 28 (7). 793 - 800. ISSN 0951-4198

Shepherd, DA, Holmes, K, Rowlands, DJ, Stonehouse, NJ and Ashcroft, AE (2013) Using ion mobility spectrometry-mass spectrometry to decipher the conformational and assembly characteristics of the hepatitis B capsid protein. Biophysical Journal, 105 (5). 1258 - 1267. ISSN 0006-3495

Sheynis, T, Friediger, A, Xue, W-F, Hellewell, AL, Tipping, KW, Hewitt, EW, Radford, SE and Jelinek, R (2013) Aggregation modulators interfere with membrane interactions of β2-microglobulin fibrils. Biophysical Journal, 105 (3). 745 - 755. ISSN 0006-3495

Shipley, S.J., Parkin, E.T., Itzhaki, R.F. and Dobson, C.B. (2005) Herpes simplex virus interferes with amyloid precursor protein processing. BMC Microbiology, 5 (48). ISSN 1471-2180

Smith, A.M., Jahn, T.R., Ashcroft, A.E. and Radford, S.E. (2006) Direct observation of oligomeric species formed in the early stages of amyloid fibril formation using mass spectrometry. Journal of Molecular Biology, 364 (1). pp. 9-19. ISSN 0022-2836

Smith, D.A., Brockwell, D.J., Zinober, R.C., Blake, A.W., Beddard, G.S., Olmsted, P.D. and Radford, S.E. (2003) Unfolding dynamics of proteins under applied force. Philosophical Transactions Of The Royal Society Of London Series A - Mathematical Physical and Engineering Sciences, 361 (1805). 713 -730. ISSN 1471-2962

Su, Y, Eddy, MT, Debelouchina, GT, Andreas, LB, Griffin, RG, Sarell, CJ, Pashley, CL and Radford, SE (2014) Secondary structure in the core of amyloid fibrils formed from human βm and its truncated variant Δn6. Journal of the American Chemical Society, 136 (17). 6313 - 6325. ISSN 0002-7863


Tan, K, Roberts, AJ, Chonofsky, M, Egan, MJ and Reck-Peterson, SL (2014) A microscopy-based screen employing multiplex genome sequencing identifies cargo-specific requirements for dynein velocity. Molecular Biology of the Cell, 25 (5). 669 - 678.

Tiede, C, Tang, AA, Deacon, SE, Mandal, U, Nettleship, JE, Owen, RL, George, SE, Harrison, DJ, Owens, RJ, Tomlinson, DC and McPherson, MJ (2014) Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications. Protein Engineering Design and Selection, 27 (5). 145 - 155 (10). ISSN 1741-0126

Trinh, C.H., Smith, D.P., Arnout, P.K., Phillips, S.E.V. and Radford, S.E. (2002) Crystal structure of monomeric human β-2- microglobulin reveals clues to its amyloidogenic properties. Proceedings of the National Academy of Sciences, 99 (15). pp. 9771-9776. ISSN 0027-8424


Vardy, E.R.L.C, Rice, P.J, Bowie, P.C.W, Holmes, J.D, Grant, P.J and Hooper, N.M (2007) Increased circulating insulin-like growth factor-1 in late-onset Alzheimer's disease. Journal of Alzheimer's Disease, 12 (4). pp. 285-290. ISSN 1387-2877


Walker, P.P., Reynolds, M.T., Ashbee, H.R., Brown, C. and Evans, E.G.V. (2000) Vaginal yeasts in the era of "over the counter" antifungals. Sexually Transmitted Infections, 76 (6). pp. 437-438. ISSN 1368-4973

Wallin, A.E., Ojala, H., Haeggstrom, E. and Tuma, R. (2008) Stiffer optical tweezers through real-time feedback control. Applied Physics Letters, 92 (22). Art. No. 224104. ISSN 0003-6951

Wilcox, M.H., Fitzgerald, P., Freeman, J., Denton, M., Gill, A.B., Hoy, C., Parnell, P., Porter, C., Haspinall, L. and Hawkey, P. (2000) A five year outbreak of methicillin-susceptible Staphylococcus aureus phage type 53,85 in a regional neonatal unit. Epidemiology and Infection, 124 (1). pp. 37-45. ISSN 0950-2688

Williams, G.J, Domann, S., Nelson, A. and Berry, A. (2003) Modifying the stereochemistry of an enzyme-catalyzed reaction by directed evolution. Proceedings of the National Academy of Sciences, 100 (6). pp. 3143-3148. ISSN 0027-8424

Wolny, M, Colegrave, M, Colman, L, White, E, Knight, P and Peckham, M (2013) Cardiomyopathy mutations in the tail of beta cardiac myosin modify the coiled-coil structure and affect integration into thick filaments in muscle sarcomeres in adult cardiomyocytes. Journal of Biological Chemistry, 288 (44). 31952 - 31962. ISSN 0021-9258

Woods, LA, Platt, GW, Hellewell, AL, Hewitt, EW, Homans, SW, Ashcroft, AE and Radford, SE (2011) Ligand binding to distinct states diverts aggregation of an amyloid-forming protein. Nature Chemical Biology, 7. 730 - 739. ISSN 1552-4469


Xue, W-F and Radford, SE (2013) An imaging and systems modeling approach to fibril breakage enables prediction of amyloid behavior. Biophysical Journal, 105 (12). 2811 - 2819. ISSN 0006-3495


Yan, R, Hallam, A, Stockley, PG and Boyes, J (2014) Oncogene dependency and the potential of targeted RNAi-based anti-cancer therapy. Biochemical Journal, 461 (1). 1 - 13. ISSN 0264-6021

Yang, S, Barbu-Tudoran, L, Orzechowski, M, Craig, R, Trinick, J, White, H and Lehman, W (2014) Three-dimensional organization of troponin on cardiac muscle thin filaments in the relaxed state. Biophysical Journal, 106 (4). 855 - 864. ISSN 0006-3495

Young, LM, Cao, P, Raleigh, DP, Ashcroft, AE and Radford, SE (2013) Ion mobility spectrometry-mass spectrometry defines the oligomeric intermediates in amylin amyloid formation and the mode of action of inhibitors. Journal of the American Chemical Society, 136 (2). 660 - 670. ISSN 1520-5126

Yuzugullu, Y, Trinh, CH, Smith, MA, Pearson, AR, Sutay Kocabas, D, Phillips, SEV, Bakir, U, Ogel, ZB and McPherson, MJ (2013) Crystal structure, recombinant expression and mutagenesis studies of the bifunctional catalase-phenol oxidase from Scytalidium thermophilum. Acta Crystallographica Section D: Biological Crystallography, 69. 398 - 408. ISSN 0365-110X

This list was generated on Sat Feb 28 13:57:43 2015 GMT.