Mewar, D., Marinou, I., Timms, J.M., Kilding, R. and Wilson, A.G. (2005) Polymorphism within the telomeric MHC and expression of rheumatoid arthritis candidate genes. In: 25th European Workshop for Rheumatology Research, 24-27 February 2005, Glasgow, UK.
Full text not available from this repository.Abstract
Several recent studies have indicated a second susceptibility locus for rheumatoid arthritis (RA) in the telomeric MHC close to the tumour necrosis factor locus, a region containing a number of genes of unknown function including HLA-B associated transcripts 1 and 2 (BAT1 and BAT2) and lymphotoxin alpha (LTA). Several single-nucleotide polymorphisms have been described in this region; however, the influence of each on susceptibility is not known. In this study we sought to examine the association of individual single-nucleotide polymorphisms with expression of each mRNA transcript in response to an inflammatory stimulus.
| Item Type: | Conference or Workshop Item (Poster) |
|---|---|
| Copyright, Publisher and Additional Information: | © 2005 BioMed Central Ltd |
| Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine (Sheffield) > Division of Genomic Medicine (Sheffield) |
| Depositing User: | Sheffield Import |
| Date Deposited: | 09 Oct 2009 09:37 |
| Last Modified: | 09 Oct 2009 09:37 |
| Published Version: | http://dx.doi.org/10.1186/ar1650 |
| Status: | Published |
| URI: | http://eprints.whiterose.ac.uk/id/eprint/9706 |
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