Gene expression signatures in motor neurone disease fibroblasts reveal dysregulation of metabolism, hypoxia-response and RNA processing functions

Raman, R., Allen, S.P., Goodall, E.F. et al. (11 more authors) (2015) Gene expression signatures in motor neurone disease fibroblasts reveal dysregulation of metabolism, hypoxia-response and RNA processing functions. Neuropathology and Applied Neurobiology, 41 (2). pp. 201-226. ISSN 0305-1846

Abstract

Metadata

Authors/Creators:
  • Raman, R.
  • Allen, S.P.
  • Goodall, E.F.
  • Kramer, S.
  • Ponger, L-L.
  • Heath, P.R.
  • Milo, M.
  • Hollinger, H.C.
  • Walsh, T.
  • Highley, J.R.
  • Olpin, S.
  • McDermott, C.J.
  • Shaw, P.J.
  • Kirby, J.
Copyright, Publisher and Additional Information: © 2014 The Authors. Neuropathology and Applied Neurobiology published by John Wiley & Sons Ltd. on behalf of British Neuropathological Society. This is an open access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Keywords: amyotrophic lateral sclerosis; cell models; fibroblasts; hypoxia response; microarray; microRNA; primary lateral sclerosis
Dates:
  • Published: February 2015
  • Accepted: 7 April 2014
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Neuroscience (Sheffield)
The University of Sheffield > Faculty of Science (Sheffield) > School of Biological Sciences (Sheffield) > Department of Biomedical Science (Sheffield)
The University of Sheffield > Sheffield Teaching Hospitals
Depositing User: Symplectic Sheffield
Date Deposited: 18 Jan 2016 10:09
Last Modified: 18 Jan 2016 10:09
Published Version: http://dx.doi.org/10.1111/nan.12147
Status: Published
Publisher: Wiley
Refereed: Yes
Identification Number: https://doi.org/10.1111/nan.12147
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