Baseler, H.E., Brewer, A.A., Sharpe, L.T., Morland, A.B., Jägle, H. and Wandell, B.A. (2002) Reorganization of human cortical maps caused by inherited photoreceptor abnormalities. Nature Neuroscience, 5 (4). pp. 364-370. ISSN 1097-6256
Full text not available from this repository.Abstract
We describe a compelling demonstration of large-scale developmental reorganization in the human visual pathways. The developmental reorganization was observed in rod monochromats, a rare group of congenitally colorblind individuals who virtually lack cone photoreceptor function. Normal controls had a cortical region, spanning several square centimeters, that responded to signals initiated in the all-cone foveola but was inactive under rod viewing conditions; in rod monochromats this cortical region responded powerfully to rod-initiated signals. The measurements trace a causal pathway that begins with a genetic anomaly that directly influences sensory cells and ultimately results in a substantial central reorganization.
| Item Type: | Article |
|---|---|
| Academic Units: | The University of York > Psychology (York) |
| Depositing User: | York RAE Import |
| Date Deposited: | 12 Mar 2009 16:21 |
| Last Modified: | 12 Mar 2009 16:21 |
| Published Version: | http://dx.doi.org/10.1038/nn817 |
| Status: | Published |
| Publisher: | Nature Publishing Group |
| Identification Number: | 10.1038/nn817 |
| URI: | http://eprints.whiterose.ac.uk/id/eprint/7101 |
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