Whitehead, D.M., Jackson, T., McKeown, S.C., Wilson, K. and Routledge, A. (2002) Application of X-ray photoelectron Sspectroscopy in determining the structure of solid-phase bound substrates. Journal Of Combinatorial Chemistry, 4 (4). pp. 255-257. ISSN 1520-4766Full text not available from this repository.
The synthesis of compounds on solid supports has grown rapidly in the past 10 years, but one of the hurdles to the routine adoption of solid-supported chemistry is the limited number of analytical methods available to characterize resin-bound compounds. There have been methods developed for on-bead reaction monitoring of solid-phase reactions; both magic angle spinning (MAS) NMR1 and FTIR2 are useful techniques, but much solid-phase chemistry still relies on releasing the product from the solid support for validation. As a result, there still remains the need for complementary techniques that could quantify and/or identify functional groups prepared during solid-phase synthesis.
|Academic Units:||The University of York > Chemistry (York)|
|Depositing User:||York RAE Import|
|Date Deposited:||23 Apr 2009 13:31|
|Last Modified:||23 Apr 2009 13:31|
|Publisher:||American Chemical Society|
Actions (login required)