Hughes, A.M., Armstrong, B.K., Vajdic, C.M., Turner, J., Grulich, A., Fritschi, L., Milliken, S., Kaldor, J., Benke, G. and Kricker, A. (2004) Pigmentary characteristics, sun sensitivity and non-Hodgkin lymphoma. International Journal of Cancer, 110 ( 3). pp. 429-434. ISSN 0020-7136
We report on pigmentary characteristics, sun sensitivity and some other possible risk factors for non-Hodgkin lymphoma (NHL) in people 20-74 years of age. A statewide case-control study was conducted in New South Wales, Australia, with population-based sampling of cases (n = 704) and controls (n = 694). Risk of NHL was increased in subjects with hazel eyes (OR = 1.48; 95% CI = 1.07-2.04), very fair skin (OR = 1.44; 95% CI = 1.01-2.07) and poor ability to tan (OR = 1.70; 95% CI = 1.06-2.71). Risk with mild facial freckling as a child (OR = 0.77; 95% CI = 0.59-0.99) was reduced relative to that with no or moderate to severe freckling. Smokers were not at increased risk of NHL. A past history of treatment for skin cancer was associated with a slight nonsignificant increase in risk. Previous radiotherapy and chemotherapy were associated with 1.5- to 2-fold increases in risk but with wide confidence intervals. These results provide weak support for the possibility that sun sensitivity or perhaps sun exposure increases risk of NHL.
|Institution:||The University of York|
|Academic Units:||The University of York > Health Sciences (York)|
|Depositing User:||York RAE Import|
|Date Deposited:||05 Aug 2009 10:49|
|Last Modified:||05 Aug 2009 10:49|
|Publisher:||John Wiley & Sons, Ltd|