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High-affinity multivalent DNA binding by using low-molecular-weight dendrons

Kostiainen, M.A., Hardy, J.G. and Smith, D.K. (2005) High-affinity multivalent DNA binding by using low-molecular-weight dendrons. Angewandte Chemie-International Edition, 44 (17). pp. 2556-2559. ISSN 1433-7851

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Abstract

Nine spermines are better than one: Compound G2 exhibits high-affinity, salt-independent DNA binding as a consequence of the spermine array on its surface. Comparison with smaller dendrons and model compounds indicates a clear multivalency effect on binding.

Item Type: Article
Institution: The University of York
Academic Units: The University of York > Chemistry (York)
Depositing User: York RAE Import
Date Deposited: 12 Aug 2009 16:20
Last Modified: 12 Aug 2009 16:20
Published Version: http://dx.doi.org/10.1002/anie.200500066
Status: Published
Publisher: John Wiley & Sons
Identification Number: 10.1002/anie.200500066
URI: http://eprints.whiterose.ac.uk/id/eprint/5480

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