High-affinity multivalent DNA binding by using low-molecular-weight dendrons

Kostiainen, M.A., Hardy, J.G. and Smith, D.K. (2005) High-affinity multivalent DNA binding by using low-molecular-weight dendrons. Angewandte Chemie-International Edition, 44 (17). pp. 2556-2559. ISSN 1433-7851

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Abstract

Nine spermines are better than one: Compound G2 exhibits high-affinity, salt-independent DNA binding as a consequence of the spermine array on its surface. Comparison with smaller dendrons and model compounds indicates a clear multivalency effect on binding.

Item Type:	Article
Academic Units:	The University of York > Chemistry (York)
Depositing User:	York RAE Import
Date Deposited:	12 Aug 2009 16:20
Last Modified:	12 Aug 2009 16:20
Published Version:	http://dx.doi.org/10.1002/anie.200500066
Status:	Published
Publisher:	John Wiley & Sons
Identification Number:	10.1002/anie.200500066
URI:	http://eprints.whiterose.ac.uk/id/eprint/5480

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