Interleukin-1 regulates CXCL8 release and influences disease outcome in response to streptococcus pneumoniae, defining intercellular cooperation between pulmonary epithelial cells and macrophages

Marriott, H. M., Gascoyne, K. A., Gowda, R., Geary, I., Nicklin, M. J. H., Iannelli, F., Pozzi, G., Mitchell, T. J., Whyte, M. K. B., Sabroe, I. and Dockrell, D. H. (2012) Interleukin-1 regulates CXCL8 release and influences disease outcome in response to streptococcus pneumoniae, defining intercellular cooperation between pulmonary epithelial cells and macrophages. Infection and Immunity, 80 (3). pp. 1140-1149. ISSN 0019-9567

Abstract

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Authors/Creators:
  • Marriott, H. M.
  • Gascoyne, K. A.
  • Gowda, R.
  • Geary, I.
  • Nicklin, M. J. H.
  • Iannelli, F.
  • Pozzi, G.
  • Mitchell, T. J.
  • Whyte, M. K. B.
  • Sabroe, I.
  • Dockrell, D. H.
Copyright, Publisher and Additional Information: © 2012 American Society of Microbiology. This is an author produced version of a paper subsequently published in Infection and Immunity. Uploaded in accordance with the publisher's self-archiving policy.
Keywords: Impaired Host-Defense; Tumor-Necrosis-Factor; Pneumococcal Pneumonia; Inflammatory Responses; Neutrophil Recruitment; Human-Monocytes; Deficient Mice; THP-1 Cells; I Receptor; Lung
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine (Sheffield) > Department of Infection & Immunity
Depositing User: Miss Anthea Tucker
Date Deposited: 21 Mar 2012 09:43
Last Modified: 08 Feb 2013 17:37
Published Version: http://dx.doi.org/10.1128/IAI.05697-11
Status: Published
Publisher: American Society for Microbiology
Refereed: Yes
Identification Number: 10.1128/IAI.05697-11

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