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Vaginal yeasts in the era of "over the counter" antifungals

Walker, P.P., Reynolds, M.T., Ashbee, H.R., Brown, C. and Evans, E.G.V. (2000) Vaginal yeasts in the era of "over the counter" antifungals. Sexually Transmitted Infections, 76 (6). pp. 437-438. ISSN 1368-4973

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OBJECTIVE: To establish whether there has been any rise in the prevalence of non-albicans Candida species isolated from vaginal swabs since the introduction of “over the counter” antifungal treatments.

METHOD: A retrospective review looking at all positive vaginal yeast isolates collected from women attending one genitourinary medicine clinic during the 6 year period from 1993 to 1998 inclusive. All positive vaginal yeast isolates were included, regardless of whether or not the patients were symptomatic. Isolates from HIV positive women were excluded from the analysis.

RESULT: No increase in non-albicans vaginal yeast isolates was shown during the period studied. The proportion of non-albicans yeasts remained constant at approximately 5% of the total yeasts isolated. The most common non-albicans yeast isolated was C glabrata.

CONCLUSION: There is no evidence from this study to suggest that the increasing use of “over the counter” antifungal treatment has selected for atypical, possibly inherently azole resistant, strains of vaginal yeasts in HIV seronegative women.

Item Type: Article
Copyright, Publisher and Additional Information: © 2000 BMJ Publishing Group
Keywords: vulvovaginal candidiasis, non-albicans species, antifungal drug resistance
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Molecular and Cellular Biology (Leeds)
Depositing User: Sherpa Assistant
Date Deposited: 13 Mar 2006
Last Modified: 18 Aug 2015 12:58
Published Version: http://sti.bmjjournals.com/cgi/content/full/76/6/4...
Status: Published
Refereed: Yes
Identification Number: 10.1136/sti.76.6.437
URI: http://eprints.whiterose.ac.uk/id/eprint/260

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