Poly(ADP-Ribose) glycohydrolase (PARG) vs. poly(ADP-Ribose) polymerase (PARP) – function in genome maintenance and relevance of inhibitors for anti-cancer therapy

Harrision, D., Gravells, P., Thompson, R. et al. (1 more author) (2020) Poly(ADP-Ribose) glycohydrolase (PARG) vs. poly(ADP-Ribose) polymerase (PARP) – function in genome maintenance and relevance of inhibitors for anti-cancer therapy. Frontiers in Molecular Biosciences, 7. 191. ISSN 2296-889X

Abstract

Metadata

Authors/Creators:
Copyright, Publisher and Additional Information: © 2020 Harrision, Gravells, Thompson and Bryant. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Keywords: poly(ADP-ribose)polymerase (PARP); poly(ADP-ribose)glycohydrolase (PARG); synthetic lethality; chemosensitization; radiosensitization; cancer
Dates:
  • Accepted: 20 July 2020
  • Published (online): 28 August 2020
  • Published: 28 August 2020
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Human Metabolism (Sheffield)
The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Oncology (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 02 Oct 2020 10:09
Last Modified: 02 Oct 2020 10:09
Status: Published
Publisher: Frontiers Media SA
Refereed: Yes
Identification Number: https://doi.org/10.3389/fmolb.2020.00191

Download

Export

Statistics