MutT homologue 1 (MTH1) removes N6-methyl-dATP from the dNTP pool

Scaletti, E.R., Vallin, K.S., Bräutigam, L. et al. (5 more authors) (2020) MutT homologue 1 (MTH1) removes N6-methyl-dATP from the dNTP pool. Journal of Biological Chemistry, 295 (15). pp. 4761-4772. ISSN 0021-9258

Abstract

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Authors/Creators:
Copyright, Publisher and Additional Information: © 2020 The Authors. Article available under a Creative Commons license (https://creativecommons.org/licenses/by/4.0/)
Keywords: MutT homologue 1 (MTH1); N6-methyl-dATP; Nudix hydrolase 1 (NUDT1); X-ray crystallography; crystal structure; enzyme catalysis; enzyme kinetics; epigenetics; hydrolase; methylation; nucleoside/nucleotide metabolism; nucleotide hydrolysis; substrate specificity
Dates:
  • Accepted: 6 March 2020
  • Published (online): 4 January 2021
  • Published: 10 April 2020
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 08 Apr 2020 06:51
Last Modified: 25 Nov 2021 14:39
Status: Published
Publisher: American Society for Biochemistry & Molecular Biology (ASBMB)
Refereed: Yes
Identification Number: https://doi.org/10.1074/jbc.ra120.012636
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