Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4

Tucker, Julie Ann orcid.org/0000-0002-6119-676X, Myers, Stephanie M., Miller, Duncan C. et al. (27 more authors) (2019) Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4. European Journal of Medicinal Chemistry. pp. 530-543. ISSN 0223-5234

Abstract

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Authors/Creators:
  • Tucker, Julie Ann ORCID logo https://orcid.org/0000-0002-6119-676X
  • Myers, Stephanie M.
  • Miller, Duncan C.
  • Molyneux, Lauren
  • Arasta, Mercedes
  • Bawn, Ruth H.
  • Blackburn, Timothy J.
  • Cook, Simon J.
  • Edwards, Noel
  • Endicott, Jane A.
  • Golding, Bernard T.
  • Griffin, Roger J.
  • Hammonds, Tim
  • Hardcastle, Ian R.
  • Harnor, Suzannah J.
  • Heptinstall, Amy B.
  • Lochhead, Pamela A.
  • Martin, Mathew P.
  • Martin, Nick C.
  • Newell, David R.
  • Owen, Paul J.
  • Pang, Leon C.
  • Reuillon, Tristan
  • Rigoreau, Laurent J.M.
  • Thomas, Huw D.
  • Wang, Lan-Zhen
  • Wong, Ai-Ching
  • Noble, Martin E.M.
  • Wedge, Stephen R.
  • Cano, Celine
Copyright, Publisher and Additional Information: © 2019 Elsevier Masson SAS. All rights reserved. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy.
Keywords: BMK1, Bioavailable, ERK5, Extracellular regulated kinase 5, Kinase, Pyrrole carboxamide
Dates:
  • Accepted: 20 May 2019
  • Published (online): 25 May 2019
  • Published: 15 September 2019
Institution: The University of York
Academic Units: The University of York > Faculty of Sciences (York) > Biology (York)
Depositing User: Pure (York)
Date Deposited: 03 Jul 2019 09:30
Last Modified: 06 Dec 2023 13:11
Published Version: https://doi.org/10.1016/j.ejmech.2019.05.057
Status: Published
Refereed: Yes
Identification Number: https://doi.org/10.1016/j.ejmech.2019.05.057
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