Tarn, Mark D., Kızılyer, Nuray Yavuzkanat, Esfahani, Mohammad M.N. et al. (5 more authors) (2018) Plastic Scintillator-Based Microfluidic Devices for Miniaturized Detection of Positron Emission Tomography Radiopharmaceuticals. Chemistry - A European Journal. pp. 13749-13753. ISSN 1521-3765
Abstract
A miniaturized radio-HPLC detector has been developed comprising a microfluidic device fabricated from plastic scintillator in combination with a silicon photomultiplier light sensor, and tested with samples containing a positron-emitting radionuclide, [18F]fluoride. This cost-effective, small footprint analytical tool is ideal for incorporation into integrated quality control systems for the testing of positron emission tomography (PET) radiopharmaceuticals to good manufacturing practice (GMP) standards.
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2018, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details. |
Keywords: | liquid chromatography, microfluidics, plastic scintillator, positron emission tomography, radiopharmaceuticals, silicon photomultiplier |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Physics (York) |
Depositing User: | Pure (York) |
Date Deposited: | 22 Jan 2019 09:40 |
Last Modified: | 06 Dec 2023 12:46 |
Published Version: | https://doi.org/10.1002/chem.201802395 |
Status: | Published |
Refereed: | Yes |
Identification Number: | https://doi.org/10.1002/chem.201802395 |
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