Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

Mavaddat, N, Michailidou, K, Dennis, J et al. (266 more authors) (2019) Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes. The American Journal of Human Genetics, 104 (1). pp. 21-34. ISSN 0002-9297

Abstract

Metadata

Authors/Creators:
  • Mavaddat, N
  • Michailidou, K
  • Dennis, J
  • Lush, M
  • Fachal, L
  • Lee, A
  • Tyrer, JP
  • Chen, T
  • Wang, Q
  • Bolla, MK
  • Yang, X
  • Adank, MA
  • Ahearn, T
  • Aittomäki, K
  • Allen, J
  • Andrulis, IL
  • Anton-Culver, H
  • Antonenkova, NN
  • Arndt, V
  • Aronson, KJ
  • Auer, PL
  • Auvinen, P
  • Barrdahl, M
  • Beane Freeman, LE
  • Beckmann, MW
  • Behrens, S
  • Benitez, J
  • Bermisheva, M
  • Bernstein, L
  • Blomqvist, C
  • Bogdanova, NV
  • Bojesen, SE
  • Bonanni, B
  • Børresen-Dale, A
  • Brauch, H
  • Bremer, M
  • Brenner, H
  • Brentnall, A
  • Brock, IW
  • Brooks-Wilson, A
  • Brucker, SY
  • Brüning, T
  • Burwinkel, B
  • Campa, D
  • Carter, BD
  • Castelao, JE
  • Chanock, SJ
  • Chlebowski, R
  • Christiansen, H
  • Clarke, CL
  • Collée, JM
  • Cordina-Duverger, E
  • Cornelissen, S
  • Couch, FJ
  • Cox, A https://orcid.org/0000-0002-5138-1099
  • Cross, SS
  • Czene, K
  • Daly, MB
  • Devilee, P
  • Dörk, T
  • dos-Santos-Silva, I
  • Dumont, M
  • Durcan, L
  • Dwek, M
  • Eccles, DM
  • Ekici, AB
  • Eliassen, AH
  • Ellberg, C
  • Engel, C
  • Eriksson, M
  • Evans, DG
  • Fasching, PA
  • Figueroa, J
  • Fletcher, O
  • Flyger, H
  • Försti, A
  • Fritschi, L
  • Gabrielson, M
  • Gago-Dominguez, M
  • Gapstur, SM
  • García-Sáenz, JA
  • Gaudet, MM
  • Georgoulias, V
  • Giles, GG
  • Gilyazova, IR
  • Glendon, G
  • Goldberg, MS
  • Goldgar, DE
  • González-Neira, A
  • Grenaker Alnæs, GI
  • Grip, M
  • Gronwald, J
  • Grundy, A
  • Guénel, P
  • Haeberle, L
  • Hahnen, E
  • Haiman, CA
  • Håkansson, N
  • Hamann, U
  • Hankinson, SE
  • Harkness, EF
  • Hart, SN
  • He, W
  • Hein, A
  • Heyworth, J
  • Hillemanns, P
  • Hollestelle, A
  • Hooning, MJ
  • Hoover, RN
  • Hopper, JL
  • Howell, A
  • Huang, G
  • Humphreys, K
  • Hunter, DJ
  • Jakimovska, M
  • Jakubowska, A
  • Janni, W
  • John, EM
  • Johnson, N
  • Jones, ME
  • Jukkola-Vuorinen, A
  • Jung, A
  • Kaaks, R
  • Kaczmarek, K
  • Kataja, V
  • Keeman, R
  • Kerin, MJ
  • Khusnutdinova, E
  • Kiiski, JI
  • Knight, JA
  • Ko, Y
  • Kosma, V
  • Koutros, S
  • Kristensen, VN
  • Krüger, U
  • Kühl, T
  • Lambrechts, D
  • Le Marchand, L
  • Lee, E
  • Lejbkowicz, F
  • Lilyquist, J
  • Lindblom, A
  • Lindström, S
  • Lissowska, J
  • Lo, W
  • Loibl, S
  • Long, J
  • Lubiński, J
  • Lux, MP
  • MacInnis, RJ
  • Maishman, T
  • Makalic, E
  • Maleva Kostovska, I
  • Mannermaa, A
  • Manoukian, S
  • Margolin, S
  • Martens, JWM
  • Martinez, ME
  • Mavroudis, D
  • McLean, C
  • Meindl, A
  • Menon, U
  • Middha, P
  • Miller, N
  • Moreno, F
  • Mulligan, AM
  • Mulot, C
  • Muñoz-Garzon, VM
  • Neuhausen, SL
  • Nevanlinna, H
  • Neven, P
  • Newman, WG
  • Nielsen, SF
  • Nordestgaard, BG
  • Norman, A
  • Offit, K
  • Olson, JE
  • Olsson, H
  • Orr, N
  • Pankratz, VS
  • Park-Simon, T
  • Perez, JIA
  • Pérez-Barrios, C
  • Peterlongo, P
  • Peto, J
  • Pinchev, M
  • Plaseska-Karanfilska, D
  • Polley, EC
  • Prentice, R
  • Presneau, N
  • Prokofyeva, D
  • Purrington, K
  • Pylkäs, K
  • Rack, B
  • Radice, P
  • Rau-Murthy, R
  • Rennert, G
  • Rennert, HS
  • Rhenius, V
  • Robson, M
  • Romero, A
  • Ruddy, KJ
  • Ruebner, M
  • Saloustros, E
  • Sandler, DP
  • Sawyer, EJ
  • Schmidt, DF
  • Schmutzler, RK
  • Schneeweiss, A
  • Schoemaker, MJ
  • Schumacher, F
  • Schürmann, P
  • Schwentner, L
  • Scott, C
  • Scott, RJ
  • Seynaeve, C
  • Shah, M
  • Sherman, ME
  • Shrubsole, MJ
  • Shu, X
  • Slager, S
  • Smeets, A
  • Sohn, C
  • Soucy, P
  • Southey, MC
  • Spinelli, JJ
  • Stegmaier, C
  • Stone, J
  • Swerdlow, AJ
  • Tamimi, RM
  • Tapper, WJ
  • Taylor, JA
  • Terry, MB
  • Thöne, K
  • Tollenaar, RAEM
  • Tomlinson, I
  • Truong, T
  • Tzardi, M
  • Ulmer, H
  • Untch, M
  • Vachon, CM
  • van Veen, EM
  • Vijai, J
  • Weinberg, CR
  • Wendt, C
  • Whittemore, AS
  • Wildiers, H
  • Willett, W
  • Winqvist, R
  • Wolk, A
  • Yang, XR
  • Yannoukakos, D
  • Zhang, Y
  • Zheng, W
  • Ziogas, A
  • Dunning, AM
  • Thompson, DJ
  • Chenevix-Trench, G
  • Chang-Claude, J
  • Schmidt, MK
  • Hall, P
  • Milne, RL
  • Pharoah, PDP
  • Antoniou, AC
  • Chatterjee, N
  • Kraft, P
  • García-Closas, M
  • Simard, J
  • Easton, DF
Copyright, Publisher and Additional Information: © 2018 The Authors. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Keywords: breast; cancer; risk; polygenic; stratification; genetic; epidemiology; screening; prediction; score
Dates:
  • Published: 3 January 2019
  • Accepted: 3 November 2018
  • Published (online): 13 December 2018
Institution: The University of Sheffield
Funding Information:
FunderGrant number
CANCER RESEARCH UKC9267/A25152
BREAST CANCER NOWTB2017SHEF
BREAST CANCER NOWTB2018SHEF
Depositing User: Symplectic Sheffield
Date Deposited: 17 Dec 2018 11:25
Last Modified: 15 Feb 2019 15:20
Status: Published
Refereed: Yes
Identification Number: https://doi.org/10.1016/j.ajhg.2018.11.002
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