Epistasis analysis uncovers hidden antibiotic resistance-associated fitness costs hampering the evolution of MRSA

Yokoyama, M, Stevens, E, Laabei, M et al. (15 more authors) (2018) Epistasis analysis uncovers hidden antibiotic resistance-associated fitness costs hampering the evolution of MRSA. Genome Biology, 19 (1). 94. 94-. ISSN 1474-760X

Abstract

Metadata

Authors/Creators:
  • Yokoyama, M
  • Stevens, E
  • Laabei, M
  • Bacon, L
  • Heesom, K
  • Bayliss, S
  • Ooi, N
  • O’Neill, AJ
  • Murray, E
  • Williams, P
  • Lubben, A
  • Reeksting, S
  • Meric, G
  • Pascoe, B
  • Sheppard, SK
  • Recker, M
  • Hurst, LD
  • Massey, RC
Copyright, Publisher and Additional Information: © The Author(s). 2018 Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Keywords: MRSA; Mupirocin resistance; Fitness costs; GWAS; Epistasis
Dates:
  • Accepted: 25 June 2018
  • Published (online): 18 July 2018
  • Published: 18 July 2018
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Molecular and Cellular Biology (Leeds) > Molecular Microbiology (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 03 Aug 2018 14:58
Last Modified: 03 Aug 2018 14:58
Status: Published
Publisher: BioMed Central
Identification Number: https://doi.org/10.1186/s13059-018-1469-2
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