Hughes, N and Stark, D orcid.org/0000-0002-6172-733X (2018) The management of adolescents and young adults with cancer. Cancer Treatment Reviews, 67. pp. 45-53. ISSN 0305-7372
Abstract
Adolescents and Young Adults (AYA) with cancer are young people developing serious illness when at the interface between the responsibilities of paediatric and adult cancer services. Personally, they are in a period of transition both biologically and in major social roles (Sawyer et al., 2018) [1]. For these and other reasons they present a unique set of clinical challenges in their management. Over the last 20 years the requirement for specific services to address their needs has been identified and this has become a growing field of research. Despite this survival rates still lag behind those of children and older adults with cancer (Gatta et al., 2009) [2].
Why do AYA patients have worse outcomes? The observation is that the reason is multifactorial with path to diagnosis, unique cancer biology, uncertainty of treatment protocol, compliance issues and poor recruitment to clinical trials all playing a part. In this review we will discuss the unique challenges faced by healthcare professionals when managing AYA patients who are commonly and accurately described as being in an ‘interface’ position.
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Copyright, Publisher and Additional Information: | (c) 2018 Elsevier Ltd. All rights reserved. This is an author produced version of a paper published in Cancer Treatment Reviews. Uploaded in accordance with the publisher's self-archiving policy | ||||||||||
Keywords: | Adolescent; Young adult; Cancer; Epidemiology; Survival; Psychosocial; Clinical trials; Biology; Training; Palliative care; Late effects; Survivorship | ||||||||||
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Institution: | The University of Leeds | ||||||||||
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cancer and Pathology (LICAP) | ||||||||||
Funding Information: |
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Depositing User: | Symplectic Publications | ||||||||||
Date Deposited: | 08 Jun 2018 12:41 | ||||||||||
Last Modified: | 07 May 2019 00:39 | ||||||||||
Status: | Published | ||||||||||
Publisher: | Elsevier | ||||||||||
Identification Number: | https://doi.org/10.1016/j.ctrv.2018.05.001 |
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Filename: AYA review - Hughes and Stark- revised 2018.pdf
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