Phylogenetic ctDNA analysis depicts early stage lung cancer evolution

Abbosh, C, Birkbak, NJ, Wilson, GA et al. (425 more authors) (2017) Phylogenetic ctDNA analysis depicts early stage lung cancer evolution. Nature, 545. pp. 446-451. ISSN 0028-0836

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Authors/Creators:
  • Abbosh, C
  • Birkbak, NJ
  • Wilson, GA
  • Jamal-Hanjani, M
  • Constantin, T
  • Salari, R
  • Quesne, JL
  • Moore, DA
  • Veeriah, S
  • Rosenthal, R
  • Marafioti, T
  • Kirkizlar, E
  • Watkins, TBK
  • McGranahan, N
  • Ward, S
  • Martinson, L
  • Riley, J
  • Fraioli, F
  • Bakir, MA
  • GrÖnroos, E
  • Zambrana, F
  • Endozo, R
  • Bi, WL
  • Fennessy, FM
  • Sponer, N
  • Johnson, D
  • Laycock, J
  • Shafi, S
  • Czyzewska-Khan, J
  • Rowan, A
  • Chambers, T
  • Matthews, N
  • Turajlic, S
  • Hiley, C
  • Lee, SM
  • Forster, MD
  • Ahmad, T
  • Falzon, M
  • Borg, E
  • Lawrence, D
  • Hayward, M
  • Kolvekar, S
  • Panagiotopoulos, N
  • Janes, SM
  • Thakrar, R
  • Ahmed, A
  • Blackhall, F
  • Summers, Y
  • Hafez, D
  • Naik, A
  • Ganguly, A
  • Kareht, S
  • Shah, R
  • Joseph, L
  • Quinn, AM
  • Crosbie, P
  • Naidu, B
  • Middleton, G
  • Langman, G
  • Trotter, S
  • Nicolson, M
  • Remmen, H
  • Kerr, K
  • Chetty, M
  • Gomersall, L
  • Fennell, DA
  • Nakas, A
  • Rathinam, S
  • Anand, G
  • Khan, S
  • Russell, P
  • Ezhil, V
  • Ismail, B
  • Irvin-sellers, M
  • Prakash, V
  • Lester, JF
  • Kornaszewska, M
  • Attanoos, R
  • Adams, H
  • Davies, H
  • Oukrif, D
  • Akarca, AU
  • Hartley, JA
  • Lowe, HL
  • Lock, S
  • Iles, N
  • Bell, H
  • Ngai, Y
  • Elgar, G
  • Szallasi, Z
  • Schwarz, RF
  • Herrero, J
  • Stewart, A
  • Quezada, SA
  • Van Loo, P
  • Dive, C
  • Lin, CJ
  • Rabinowitz, M
  • Aerts, HJWL
  • Hackshaw, A
  • Shaw, JA
  • Zimmermann, BG
  • Swanton, C
  • Jamal-Hanjani, M
  • Abbosh, C
  • Veeriah, S
  • Shafi, S
  • Czyzewska-Khan, J
  • Johnson, D
  • Laycock, J
  • Bosshard-Carter, L
  • Goh, G
  • Rosenthal, R
  • Gorman, P
  • Murugaesu, N
  • Hynds, RE
  • Wilson, G
  • Birkbak, NJ
  • Watkins, TBK
  • McGranahan, N
  • Horswell, S
  • Al Bakir, M
  • GrÖnroos, E
  • Mitter, R
  • Escudero, M
  • Stewart, A
  • Van Loo, P
  • Rowan, A
  • Xu, H
  • Turajlic, S
  • Hiley, C
  • Goldman, J
  • Stone, RK
  • Denner, T
  • Matthews, N
  • Elgar, G
  • Ward, S
  • Biggs, J
  • Costa, M
  • Begum, S
  • Phillimore, B
  • Chambers, T
  • Nye, E
  • Graca, S
  • Al Bakir, M
  • Joshi, K
  • Furness, A
  • Aissa, AB
  • Wong, YNS
  • Georgiou, A
  • Quezada, S
  • Hartley, JA
  • Lowe, HL
  • Herrero, J
  • Lawrence, D
  • Hayward, M
  • Panagiotopoulos, N
  • Kolvekar, S
  • Falzon, M
  • Borg, E
  • Marafioti, T
  • Simeon, C
  • Hector, G
  • Smith, A
  • Aranda, M
  • Novelli, M
  • Oukrif, D
  • Akarca, AU
  • Janes, SM
  • Thakrar, R
  • Forster, M
  • Ahmad, T
  • Lee, SM
  • Papadatos-Pastos, D
  • Carnell, D
  • Mendes, R
  • George, J
  • Navani, N
  • Ahmed, A
  • Taylor, M
  • Choudhary, J
  • Summers, Y
  • Califano, R
  • Taylor, P
  • Shah, R
  • Krysiak, P
  • Rammohan, K
  • Fontaine, E
  • Booton, R
  • Evison, M
  • Crosbie, P
  • Moss, S
  • Idries, F
  • Joseph, L
  • Bishop, P
  • Chaturved, A
  • Marie Quinn, A
  • Doran, H
  • leek, A
  • Harrison, P
  • Moore, K
  • Waddington, R
  • Novasio, J
  • Blackhall, F
  • Rogan, J
  • Smith, E
  • Dive, C
  • Tugwood, J
  • Brady, G
  • Rothwell, DG
  • Chemi, F
  • Pierce, J
  • Gulati, S
  • Naidu, B
  • Langman, G
  • Trotter, S
  • Bellamy, M
  • Bancroft, H
  • Kerr, A
  • Kadiri, S
  • Webb, J
  • Middleton, G
  • Djearaman, M
  • Fennell, D
  • Shaw, JA
  • Le Quesne, J
  • Moore, D
  • Thomas, A
  • Walter, H
  • Riley, J
  • Martinson, L
  • Nakas, A
  • Rathinam, S
  • Monteiro, W
  • Marshall, H
  • Nelson, L
  • Bennett, J
  • Riley, J
  • Primrose, L
  • Martinson, L
  • Anand, G
  • Khan, S
  • Amadi, A
  • Nicolson, M
  • Kerr, K
  • Palmer, S
  • Remmen, H
  • Miller, J
  • Buchan, K
  • Chetty, M
  • Gomersall, L
  • Lester, J
  • Edwards, A
  • Morgan, F
  • Adams, H
  • Davies, H
  • Kornaszewska, M
  • Attanoos, R
  • Lock, S
  • Verjee, A
  • MacKenzie, M
  • Wilcox, M
  • Bell, H
  • Iles, N
  • Hackshaw, A
  • Ngai, Y
  • Smith, S
  • Gower, N
  • Ottensmeier, C
  • Chee, S
  • Johnson, B
  • Alzetani, A
  • Shaw, E
  • Lim, E
  • De Sousa, P
  • Tavares Barbosa, M
  • Bowman, A
  • Jordan, S
  • Rice, A
  • Raubenheimer, H
  • Proli, C
  • Elena Cufari, M
  • Ronquillo, JC
  • Kwayie, A
  • Bhayani, H
  • Hamilton, M
  • Bakar, Y
  • Mensah, N
  • Ambrose, L
  • Devaraj, A
  • Buderi, S
  • Finch, J
  • Azcarate, L
  • Chavan, H
  • Green, S
  • Mashinga, H
  • Nicholson, AG
  • Lau, K
  • Sheaff, M
  • Schmid, P
  • Conibear, J
  • Ezhil, V
  • Ismail, B
  • Irvin-sellers, M
  • Prakash, V
  • Russell, P
  • Light, T
  • Horey, T
  • Danson, S
  • Bury, J
  • Edwards, J https://orcid.org/0000-0002-7935-5327
  • Hill, J
  • Matthews, S
  • Kitsanta, Y
  • Suvarna, K
  • Fisher, P
  • Keerio, AD
  • Shackcloth, M
  • Gosney, J
  • Postmus, P
  • Feeney, S
  • Asante-Siaw, J
  • Constatin, T
  • Salari, R
  • Sponer, N
  • Naik, A
  • Zimmermann, B
  • Rabinowitz, M
  • Aerts, HJWL
  • Dentro, S
  • Dessimoz, C
  • Swanton, C
  • Jamal-Hanjani, M
  • Abbosh, C
  • Shiu, K-K
  • Bridgewater, J
  • Hochauser, D
  • Van Loo, P
  • Quezada, S
  • Beck, S
  • Parker, P
  • Walczak, H
  • Enver, T
  • Falzon, M
  • Proctor, I
  • Sinclair, R
  • Lok, C-W
  • Novelli, M
  • Marafioti, T
  • Borg, E
  • Mitchison, M
  • Trevisan, G
  • Lynch, M
  • Brandner, S
  • Gishen, F
  • Tookman, A
  • Stone, P
  • Sterling, C
  • Larkin, J
  • Turajlic, S
  • Attard, G
  • Eeles, R
  • Foster, C
  • Bova, S
  • Sottoriva, A
  • Chowdhury, S
  • Ashish, C
  • Spicer, J
  • Stares, M
  • Lynch, J
  • Caldas, C
  • Brenton, J
  • Fitzgerald, R
  • Jimenez-Linan, M
  • Provenzano, E
  • Cluroe, A
  • Stewart, G
  • Watts, C
  • Gilbertson, R
  • McDermott, U
  • Tavare, S
  • Maughan, T
  • Tomlinson, I
  • Campbell, P
  • McNeish, I
  • Biankin, A
  • Chambers, A
  • Fraser, S
  • Oien, K
  • Krebs, M
  • Blackhall, F
  • Summers, Y
  • Dive, C
  • Marais, R
  • Carter, L
  • Nonaka, D
  • Quinn, AM
  • Dhomen, N
  • Fennell, D
  • Le Quesne, J
  • Moore, D
  • Shaw, J
  • Naidu, B
  • Baijal, S
  • Tanchel, B
  • Langman, G
  • Collard, M
  • Cockcroft, P
  • Taylor, J
  • Bancroft, H
  • Kerr, A
  • Middleton, G
  • Webb, J
  • Kadiri, S
  • Colloby, P
  • Olisemeke, B
  • Wilson, R
  • Ottensmeier, C
  • Harrison, D
  • Loda, M
  • Flanagan, A
  • Wilcox, M
  • McKenzie, M
  • Hackshaw, A
  • Lederman, J
  • Sharp, A
  • Farrelly, L
  • Swanton, C
Copyright, Publisher and Additional Information: © 2018 Nature Publishing Group.
Keywords: Diagnostic markers; Metastasis; Non-small-cell lung cancer; Predictive markers; Tumour heterogeneity
Dates:
  • Published: 26 April 2017
  • Published (online): 26 April 2017
  • Accepted: 13 April 2017
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Sheffield Teaching Hospitals
Depositing User: Symplectic Sheffield
Date Deposited: 31 May 2018 14:03
Last Modified: 31 May 2018 16:31
Published Version: https://doi.org/10.1038/nature22364
Status: Published
Publisher: Nature Publishing Group
Refereed: Yes
Identification Number: https://doi.org/10.1038/nature22364

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