Structural Insights into the Recovery of Aldolase Activity in N -Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with γ-Thialysine by Using a Chemical Mutagenesis Strategy

Timms, N, Windle, CL, Polyakova, A et al. (5 more authors) (2013) Structural Insights into the Recovery of Aldolase Activity in N -Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with γ-Thialysine by Using a Chemical Mutagenesis Strategy. ChemBioChem, 14 (4). pp. 474-481. ISSN 1439-4227

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Copyright, Publisher and Additional Information: © 2013 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim. Re-use of this article is permitted in accordance with the Terms and Conditions set out at http://chembiochem.org/open.
Keywords: aldolases; enzyme catalysis; N‐acetylneuraminic acid lyase; thialysine; unnatural amino acids
Dates:
  • Published: 4 March 2013
  • Published (online): 18 February 2013
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Molecular and Cellular Biology (Leeds) > Biomolecular Mass Spectroscopy (Leeds)
The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Molecular and Cellular Biology (Leeds) > Synthetic Biology (Leed)
The University of Leeds > Faculty of Maths and Physical Sciences (Leeds) > School of Chemistry (Leeds) > Organic Chemistry (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 08 Apr 2019 14:55
Last Modified: 08 Apr 2019 14:55
Status: Published
Publisher: Wiley
Identification Number: https://doi.org/10.1002/cbic.201200714
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