Affimer proteins inhibit immune complex binding to FcγRIIIa with high specificity through competitive and allosteric modes of action

Robinson, JI orcid.org/0000-0001-5425-7520, Baxter, EW, Owen, RL et al. (13 more authors) (2018) Affimer proteins inhibit immune complex binding to FcγRIIIa with high specificity through competitive and allosteric modes of action. Proceedings of the National Academy of Sciences, 115 (1). E72-E81. ISSN 0027-8424

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Authors/Creators:
Copyright, Publisher and Additional Information: © 2017 The Authors. This is an author produced version of a paper published in Proceedings of the National Academy of Sciences. Uploaded in accordance with the publisher's self-archiving policy. In order to comply with the publisher requirements the University does not require the author to sign a nonexclusive licence for this paper.
Keywords: Fc gamma receptor IIIa; specific inhibitor; Affimer; allosteric; competitive
Dates:
  • Published: 2 January 2018
  • Accepted: 17 November 2017
  • Published (online): 15 December 2017
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Biomedical Sciences (Leeds)
The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Molecular and Cellular Biology (Leeds) > Synthetic Biology (Leed)
The University of Leeds > Faculty of Maths and Physical Sciences (Leeds) > School of Chemistry (Leeds) > Organic Chemistry (Leeds)
The University of Leeds > Faculty of Maths and Physical Sciences (Leeds) > School of Physics and Astronomy (Leeds) > Theoretical Physics (Leeds)
Funding Information:
FunderGrant number
Arthritis Research UK19764
Depositing User: Symplectic Publications
Date Deposited: 20 Dec 2017 14:21
Last Modified: 15 May 2018 00:38
Status: Published
Publisher: National Academy of Sciences
Identification Number: https://doi.org/10.1073/pnas.1707856115

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