Alteration in intracellular Zn2+ homeostasis as a result of TRPM2 channel activation contributes to ROS-induced hippocampal neuronal death

Li, X, Yang, W and Jiang, L-H orcid.org/0000-0001-6398-0411 (2017) Alteration in intracellular Zn2+ homeostasis as a result of TRPM2 channel activation contributes to ROS-induced hippocampal neuronal death. Frontiers in Molecular Neuroscience, 10. 414. ISSN 1662-5099

Abstract

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Authors/Creators:
Copyright, Publisher and Additional Information: Copyright © 2017 Li, Yang and Jiang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Keywords: TRPM2 channel, hippocampal neuronal death, ROS, Zn2+ homeostasis, lysosomal dysfunction, Mitochondrial dysfunction
Dates:
  • Published: December 2017
  • Accepted: 29 November 2017
  • Published (online): 12 December 2017
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Biomedical Sciences (Leeds)
Funding Information:
FunderGrant number
Alzheimer's Research UKART/PPG2009A/2
Depositing User: Symplectic Publications
Date Deposited: 06 Dec 2017 09:38
Last Modified: 16 Jan 2018 15:07
Status: Published
Publisher: Frontiers Media
Identification Number: https://doi.org/10.3389/fnmol.2017.00414

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