Integration of Genome Scale Metabolic Networks and gene regulation of metabolic enzymes with Physiologically Based Pharmacokinetics

Maldonado, EM, Leoncikas, V, Fisher, CP et al. (3 more authors) (2017) Integration of Genome Scale Metabolic Networks and gene regulation of metabolic enzymes with Physiologically Based Pharmacokinetics. CPT: Pharmacometrics & Systems Pharmacology, 6 (11). pp. 732-746. ISSN 2163-8306

Abstract

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Authors/Creators:
Copyright, Publisher and Additional Information: © 2017 The Authors. CPT: Pharmacometrics & Systems Pharmacology published by Wiley Periodicals, Inc. on behalf of American Society for Clinical Pharmacology and Therapeutics. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Keywords: PBPK; GSMN; CBM; FBA; QSSPN; MUFINS; gene regulation; multiscale; systems biology
Dates:
  • Published: 1 November 2017
  • Accepted: 28 July 2017
  • Published (online): 7 August 2017
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds)
The University of Leeds > Faculty of Maths and Physical Sciences (Leeds) > School of Food Science and Nutrition (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 14 Aug 2017 14:54
Last Modified: 30 Jan 2018 14:36
Status: Published
Publisher: Wiley
Identification Number: https://doi.org/10.1002/psp4.12230

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