Jin, Saimeng, Byrne, Fergal, McElroy, Con Robert orcid.org/0000-0003-2315-8153 et al. (3 more authors) (2017) Challenges in the development of bio-based solvents : A case study on methyl(2,2-dimethyl-1,3-dioxolan-4-yl)methyl carbonate as an alternative aprotic solvent. FARADAY DISCUSSIONS. pp. 157-173. ISSN 1359-6640
Abstract
Many traditional solvents have drawbacks including sustainability and toxicity issues. Legislations such as REACH is driving the move towards less hazardous chemicals and production processes. Therefore, safer bio-based solvents need to be developed. Herein, a 10 step method has been proposed for the development of new bio-based solvents that utilise a combination of in silico modelling of Hansen solubility parameters (HSPs), experimental Kamlet-Abboud-Taft parameters, selection of green synthetic routes followed by applications testing and toxicity measurements. The challenges that the chemical industry face in the development of new bio-based solvents are highlighted through a case study on methyl (2,2-dimethyl-1,3-dioxolan-4-yl) methyl carbonate (MMC) which can be synthesised from glycerol. Although MMC is an attractive candidate as a replacement solvent, simply being bio-derived is not enough for a molecule to be regarded as green. The methodology of solvent development described here is a broadly applicable protocol that will indicate if a new bio-based solvent is functionally proficient, but will also highlight the importance of early stage Kamlet-Abboud-Taft parameters determination and toxicity testing in the development of a green solvent.
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © Royal Society of Chemistry 2017. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details. |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Chemistry (York) |
Depositing User: | Pure (York) |
Date Deposited: | 14 Mar 2017 11:00 |
Last Modified: | 06 Jan 2024 00:27 |
Published Version: | https://doi.org/10.1039/c7fd00049a |
Status: | Published |
Refereed: | Yes |
Identification Number: | https://doi.org/10.1039/c7fd00049a |
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Filename: MMC_paper_submitted_16_2_17.pdf
Description: MMC paper submitted 16-2-17