Detection of Ligand-induced Conformational Changes in the Activation Loop of Aurora-A Kinase by PELDOR Spectroscopy

Burgess, SG, Grazia Concilio, M, Bayliss, R orcid.org/0000-0003-0604-2773 et al. (1 more author) (2016) Detection of Ligand-induced Conformational Changes in the Activation Loop of Aurora-A Kinase by PELDOR Spectroscopy. ChemistryOpen, 5 (6). pp. 531-534.

Abstract

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Authors/Creators:
Copyright, Publisher and Additional Information: © 2016 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License https://creativecommons.org/licenses/by-nc/4.0/ , which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
Keywords: drug design; electron paramagnetic resonance; inhibitor; PELDOR spectroscopy; protein kinases
Dates:
  • Accepted: 5 September 2016
  • Published (online): 11 November 2016
  • Published: December 2016
Institution: The University of Leeds
Funding Information:
FunderGrant number
Cancer Research UKC24461/A12772
Depositing User: Symplectic Publications
Date Deposited: 06 Jan 2017 15:52
Last Modified: 05 Oct 2017 16:17
Published Version: https://doi.org/10.1002/open.201600101
Status: Published
Publisher: Wiley
Identification Number: https://doi.org/10.1002/open.201600101

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