Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation

Soukarieh, F., Nowicki, M.W., Bastide, A. et al. (9 more authors) (2016) Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation. European Journal of Medicinal Chemistry, 124. pp. 200-217. ISSN 0223-5234

Abstract

Metadata

Authors/Creators:
  • Soukarieh, F.
  • Nowicki, M.W.
  • Bastide, A.
  • Pöyry, T.
  • Jones, C.
  • Dudek, K.
  • Patwardhan, G.
  • Meullenet, F.
  • Oldham, N.J.
  • Walkinshaw, M.D.
  • Willis, A.E.
  • Fischer, P.M.
Copyright, Publisher and Additional Information: © 2016 The Authors. Published by Elsevier Masson SAS. This is an open access article under the CC BY license ( http://creativecommons.org/licenses/by/4.0/ ).
Keywords: Cancer; eIF4E; Protein synthesis; mRNA translation; Cap-binding inhibitor
Dates:
  • Published: 29 November 2016
  • Accepted: 21 August 2016
  • Published (online): 24 August 2016
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Engineering (Sheffield) > Department of Chemical and Biological Engineering (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 21 Dec 2016 15:35
Last Modified: 21 Dec 2016 15:36
Published Version: https://doi.org/10.1016/j.ejmech.2016.08.047
Status: Published
Publisher: Elsevier
Refereed: Yes
Identification Number: https://doi.org/10.1016/j.ejmech.2016.08.047

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