Farnesyl diphosphate synthase, the target for nitrogen-containing bisphosphonate drugs, is a peroxisomal enzyme in the model system Dictyostelium discoideum

Nuttall, J. M., Hettema, E. H. and Watts, D. J. (2012) Farnesyl diphosphate synthase, the target for nitrogen-containing bisphosphonate drugs, is a peroxisomal enzyme in the model system Dictyostelium discoideum. Biochemical Journal, 447 (3). pp. 353-361. ISSN 0264-6021

Abstract

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Authors/Creators:
  • Nuttall, J. M.
  • Hettema, E. H.
  • Watts, D. J.
Copyright, Publisher and Additional Information: © 2012 The Author(s) This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial Licence (http://creativecommons.org/licenses/by-nc/2.5/) which permits unrestricted non-commercial use, distribution and reproduction in any medium, provided the original work is properly cited.
Keywords: Dictyostelhan discoideum; farnesyl diphosphate synthase; mevalonate pathway; nitrogen-containing bisphosphonate drugs; peroxisomal targeting signal; peroxisome
Dates:
  • Published: 1 November 2012
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Science (Sheffield) > School of Biological Sciences (Sheffield) > Department of Biomedical Science (Sheffield)
The University of Sheffield > Faculty of Science (Sheffield) > School of Biological Sciences (Sheffield) > Department of Molecular Biology and Biotechnology (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 05 Dec 2016 14:23
Last Modified: 05 Dec 2016 14:25
Published Version: http://dx.doi.org/10.1042/BJ20120750
Status: Published
Publisher: Portland Press
Refereed: Yes
Identification Number: https://doi.org/10.1042/BJ20120750
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