Farmer, A., Wade, A., Goyder, E. et al. (6 more authors) (2007) Impact of self monitoring of blood glucose in the management of patients with non-insulin treated diabetes: open parallel group randomised trial. British Medical Journal (BMJ), 335. p. 132. ISSN 0959-8138
Objective: To determine whether self monitoring, alone or with instruction in incorporating the results into self care,is more effective than usual care in improving glycaemic control in non-insulin treated patients with type 2 diabetes.
Design: Three arm, open, parallel group randomised trial. Setting 48 general practices in Oxfordshire and South Yorkshire.
Participants: 453 patients with non-insulin treated type 2 diabetes (mean age 65.7 years) for a median duration of three years and a mean haemoglobin A1c level of 7.5%. Interventions Standardised usual care with measurements of HbA1c every three months as the control group (n=152), blood glucose self monitoring with advice for patients to contact their doctor for interpretation of results, in addition to usual care (n=150), and blood glucose self monitoring with additional training of patients in interpretation and application of the results to enhance motivation and maintain adherence to a healthy lifestyle (n=151).
Main outcome measure: HbA1c level measured at 12 months.
Results: At 12 months the differences in HbA1c level between the three groups (adjusted for baseline HbA1c level) were not statistically significant (P=0.12). The difference in unadjusted mean change in HbA1c level from baseline to 12 months between the control and less intensive self monitoring groups was −0.14% (95% confidence interval −0.35% to 0.07%) and between the control and more intensive self monitoring groups was −0.17% (−0.37% to 0.03%).
Conclusions: Evidence is not convincing of an effect of self monitoring blood glucose, with or without instruction in incorporating findings into self care, in improving glycaemic control compared with usual care in reasonably well controlled non-insulin treated patients with type 2 diabetes.
Trial registration Current Controlled Trials ISRCTN47464659.
|Copyright, Publisher and Additional Information:||© 2007 BMJ. Reproduced in accordance with the publisher's self-archiving policy.|
|Institution:||The University of Sheffield|
|Academic Units:||The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Health and Related Research (Sheffield) > Section of Public Health (Sheffield)|
|Depositing User:||Mrs Vivienne Walker|
|Date Deposited:||22 Mar 2010 09:52|
|Last Modified:||06 Jun 2014 00:44|
|Publisher:||BMJ Publishing Group|