DNA Polymerase Conformational Dynamics and the Role of Fidelity-Conferring Residues: Insights from Computational Simulations

Meli, M., Sustarsic, M., Craggs, T.D. et al. (2 more authors) (2016) DNA Polymerase Conformational Dynamics and the Role of Fidelity-Conferring Residues: Insights from Computational Simulations. Frontiers in Molecular Biosciences, 3.

Abstract

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Authors/Creators:
  • Meli, M.
  • Sustarsic, M.
  • Craggs, T.D.
  • Kapanidis, A.N.
  • Colombo, G.
Copyright, Publisher and Additional Information: © 2016 Meli, Sustarsic, Craggs, Kapanidis and Colombo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Keywords: DNA polymerase I; allostery; molecular dynamics simulations; molecular recognition; replication fidelity
Dates:
  • Published: 27 May 2016
  • Accepted: 10 May 2016
  • Published (online): 27 May 2016
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Science (Sheffield) > Department of Chemistry (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 07 Nov 2016 14:39
Last Modified: 07 Nov 2016 14:46
Published Version: http://dx.doi.org/10.3389/fmolb.2016.00020
Status: Published
Publisher: Frontiers Media
Refereed: Yes
Identification Number: https://doi.org/10.3389/fmolb.2016.00020
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